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Found 15 clinical trials
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NUVOLA TRIAL Open-label Multicentre Study

peritoneal tumour load. Nonetheless, BRCAmut women additionally show a higher benefit of platinum-based neoadjuvant chemotherapy (NACT) plus interval debulking surgery compared with BRCAwt women in

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Comparative Effectiveness of HIPEC Following Interval Debulking Surgery in Patients With Advanced-stage Ovarian Cancer

status. Neoadjuvant chemotherapy(NAC) followed interval debulking surgery (IDS) is an alternative therapeutic option for these patients. There is growing interest in the use of HIPEC (hyperthermic

ovarian epithelial carcinoma
peritoneal cancer
cytoreductive surgery
ovarian cancer stage
ovarian epithelial cancer
  • 8 views
  • 23 Jan, 2021
  • 1 location
None
Prehabilitation in Patients With Advanced Stage Ovarian Cancer Planned for Interval Debulking Surgery

There is a strong evidence of positive effect of multimodal prehabilitation from prospective controlled trials among patients treated surgically for non-gynaecological cancer. However, the number of studies published on prehabilitation programs in gynaecologic surgery are limited, especially in gynaecologic cancer patients. No study or trial comprehensively evaluating a prehabilitation pathway …

  • 0 views
  • 16 Mar, 2021
  • 1 location
None
Reduction Of Cycles of neOadjuvant Chemotherapy for Advanced Epithelial Ovarian Fallopian and Primary Peritoneal Cancer

Te hypothesized that two cycles of neoadjuvant chemotherapy followed by interval debulking surgery would improve survival in advanced epithelial ovarian, fallopian, and primary peritoneal cancer

metastasis
peritoneal cancer
cytoreductive surgery
cancer
remission
  • 45 views
  • 23 Jan, 2021
None
Using Aspirin to Improve Immunological Features of Ovarian Tumors

The purpose of the study is to evaluate the effectiveness of aspirin with neoadjuvant chemotherapy for decreasing markers of immune suppression in the tumor at interval debulking surgery, in

metastasis
platelet count
aspirin
taxane
fallopian tube
  • 0 views
  • 03 Nov, 2021
  • 1 location
None
Niraparib Maintenance in Patients With Advanced Ovarian Cancer at Neoadjuvant Setting

This study aims to evaluate the effects of niraparib in those who have received neoadjuvant chemotherapy and subsequent interval debulking surgery, with or without hyperthermic intraperitoneal

cytoreductive surgery
parp inhibitor
carboplatin
immunostimulant
platinum-based chemotherapy
  • 0 views
  • 06 Oct, 2021
  • 1 location
None
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI)

(PDS) or Interval Debulking Surgery (IDS), in patients with ovarian cancer. This study aims to assess the efficacy, in terms of disease-free survival (DFS), the use of HIPEC combined with standard care

endometrioid carcinoma
ovarian epithelial carcinoma
mucinous adenocarcinoma
targeted therapy
cytoreduction
  • 3 views
  • 03 Nov, 2021
  • 19 locations
None
Ovarian Cancer Treatment With a Liposome Formulated mRNA Vaccine in Combination With (Neo-)Adjuvant Chemotherapy

surgery. [18F]FB-IL2 PET-CT will be used for the non-invasive assessment of T-cell activation and correlated to immunohistochemistry tumor tissue data from pre-treatment biopsy and interval debulking

carboplatin/paclitaxel
carboplatin
cancer of the ovary
ascites
tumor debulking
  • 2 views
  • 23 May, 2021
  • 1 location
None
Paclitaxel i.v. Plus Cisplatin i.p for NACT in Patients With Advanced Ovarian Cancer

arm clinical trial. Included patients will receive interval debulking surgery after 2-6 cycles neoadjuvant chemotherapy based on the clinical judgment of the gynecologic oncologist. Six cycles of

  • 0 views
  • 18 Aug, 2021
  • 1 location
None
Study of Upfront Surgery Versus Neoadjuvant Chemotherapy in Patients With Advanced Ovarian Cancer (SUNNY)

The purpose of this study is to answer the fundamental question, should the physicians choose Surgery or Chemotherapy (SOC-2) in advanced ovarian cancer?

serum ca-125
ovarian epithelial carcinoma
cytoreductive surgery
debulking surgery
ovarian epithelial cancer
  • 505 views
  • 22 Oct, 2021
  • 7 locations