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Found 181 clinical trials
Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

The goal of this study is to investigate the efficacy of [68Ga]CBP8 to detect collagen deposition in radiation induced tissue injury.

pulmonary resection
cancer
pdac
lung resections
chemoradiotherapy
  • 0 views
  • 26 Mar, 2022
  • 1 location
Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.

This is a prospective observational study aiming: 1) To quantify lung function using perfusion dual energy computed tomography (DECT) and use this information at the time of treatment planning with preferential sparing of functional lung parenchymal 2) to validate results of lung function obtained using DECT with lung perfusion scintigraphy …

  • 0 views
  • 10 May, 2021
  • 1 location
Hydroxychloroquine in ANCA Vasculitis Evaluation

The purpose of this study is to find out whether hydroxychloroquine, in addition to background treatments, reduces disease activity in patients with Anti-Neutrophilic Cytoplasmic Autoantibodies (ANCA) Vasculitis, a group of autoimmune diseases. Hydroxychloroquine and is an established, effective, safe and inexpensive therapy, widely used in other autoimmune diseases such as …

  • 0 views
  • 26 Jan, 2021
  • 3 locations
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer (ASPECT)

Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them …

cancer
metastasis
lung carcinoma
lung cancer
diagnostic procedures
  • 0 views
  • 04 Jun, 2022
  • 1 location
Validation of the Risk Stratification Score in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by a poor prognosis, with a progressive decline in lung function and a considerable variability in the disease's natural history. Besides lung transplantation (LTx), the only available treatments are anti-fibrosing drugs, which have shown to slower the disease course. Therefore, predicting the prognosis is …

pulmonary function test
hypertension
idiopathic pulmonary fibrosis
lung transplant
emphysema
  • 138 views
  • 25 Nov, 2021
  • 2 locations
Systemic Sclerosis and Jak Inhibitors : Emphasis on Macrophages

The Sclero-JAK project aims to assess the impact of a JAK1/2 inhibitor (ruxolitinib) on activation states of monocytes-derived macrophages (MDM) from systemic sclerosis (SSc) patients

  • 8 views
  • 26 Mar, 2021
  • 1 location
LYNPARZA Pancreas Cancer Japan Post-Marketing Surveillance (PMS)

To collect and characterise the incidence of adverse events related to the safety specifications of the maintenance treatment after platinum-based chemotherapy in patients with BRCA mutated pancreatic cancer under the actual post-marketing use of LYNPAZA.

cancer chemotherapy
  • 9 views
  • 14 Jun, 2022
  • 22 locations
Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

This is a single centre exploratory study that aims to apply hyperpolarized xenon-129 (129Xe) magnetic resonance imaging (MRI) methods and measurements in individual patients with and without lung disease to better understand lung structure and function and evaluate response to therapy delivered as a part of clinical care.

pulmonary fibrosis
malnourished
pulmonary disease
COPD
bronchiectasis
  • 547 views
  • 27 Feb, 2022
  • 1 location
Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis

Respiratory muscle strength, dyspnea perception, physical activity and quality of life measurements will be performed and groups will be compared in two groups consisting of patients with idiopathic pulmonary fibrosis referred to pulmonary rehabilitation clinic and healthy volunteers in similar age range.

Accepts healthy volunteers
pulmonary rehabilitation
idiopathic pulmonary fibrosis
dyspnea
  • 19 views
  • 14 Feb, 2022
  • 1 location
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF) (GAP)

The purpose of the study is to identify genetic and biologic markers that may predict the loss of lung function due to idiopathic pulmonary fibrosis. The studies will compare genetic and biologic markers of samples to changes in symptoms. The ultimate goal is to predict if or when patients are …

idiopathic pulmonary fibrosis
pulmonary function test
  • 39 views
  • 23 Jan, 2022
  • 1 location