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Found 171 clinical trials
Pulmonary Function Assessment and Evaluation Using Self-administrable and Portable Electrical Impedance Tomography

interstitial lung diseases on anti-fibrotic. EIT can also be a more comfortable alternative to spirometry for patients who need lung function assessment.

pulmonary function test
spirometry
assisted ventilation
  • 0 views
  • 11 May, 2022
  • 1 location
The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial

Prospective clinical pilot study for subjects diagnosed with Occupational Progressive Pneumoconiosis. Subjects will be treated with Nintedanib 150mg twice daily for 3 years.

  • 1 views
  • 19 Feb, 2021
  • 1 location
Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis

This is a prospective, randomized, non-blinded, multi-center, non-inferiority trial designed to compare effectiveness and side-effects of methotrexate versus prednisolone as first-line therapy for pulmonary sarcoidosis..

  • 0 views
  • 30 Aug, 2021
  • 18 locations
TCM for Coal Worker's Pneumoconiosis

This study aims to evaluate the clinical efficacy of traditional Chinese medicine in the treatment of pneumoconiosis and to provide high-quality evidence for the prevention and treatment of pneumoconiosis.

  • 0 views
  • 20 Apr, 2021
  • 1 location
An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis (NABS)

In the diagnosis of patients with sarcoidosis, there is paucity of literature on the diagnostic yield of the endobronchial biopsies obtained with narrow band imaging (NBI) bronchoscopy. The present study aims to compare the diagnostic yield of endobronchial biopsyperformed under direct narrow band imaging or white light bronchoscopy guidance in …

  • 0 views
  • 30 Apr, 2022
  • 1 location
  • 0 views
  • 18 Sep, 2022
  • 4 locations
Endobronchial Ultrasound Strain Elastography in Sarcoidosis

Strain elastography (SE) is an imaging method used for the measurement of relative tissue elasticity through qualitative (color pattern) or semi-quantitative methods (strain ratio or strain histogram). Very recently, the first pilot study has provided preliminary evidence that EBUS-SE elastography may help identify fibrotic lymph nodes in sarcoidosis and that …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA

The aim of this study is to identify the optimal maintenance therapy for granulomatosis with polyangiitis (GPA) by comparing the MTX (standard regimen) with Tofacitinib in terms of efficacy, i.e. in preventing relapses.

  • 0 views
  • 16 Jul, 2021
  • 1 location
The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach (TAPIR)

This study is a multi-center randomized controlled trial to evaluate the effects of using low-dose prednisone as compared to stopping prednisone treatment entirely. Participants will be randomized 1:1 to taper their prednisone dose down to 5 mg/day or to 0 mg/day for the duration of the study (approximately six months) …

cavities
kidney biopsy
leflunomide
rituximab
6-mercaptopurine
  • 2 views
  • 24 Mar, 2022
  • 6 locations
Pirfenidone for the Reduction of Metabolic, Inflammatory and Fibrogenic Activity in Complicated Silicosis

Silicosis is one of the leading causes of occupational respiratory disease worldwide. It is due to inhalation of respirable crystalline silica and can lead to progressive massive fibrosis (PMF), respiratory failure, and death. It is estimated that it causes more than 10,000 deaths a year worldwide, mainly in developing countries, …

  • 0 views
  • 25 Mar, 2022