Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 60 clinical trials
Hydrogen Therapy in Patients With Moderate Covid-19 (H2Covid)

under mechanical ventilation in the intensive care unit and is responsible for the majority of deaths. Certain biological parameters suggest a massive and brutal release of cytokines (interleukins IL-6

  • 0 views
  • 08 Jun, 2022
  • 1 location
The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients. (Dexa)

Glucocorticoids are well known for their analgesic, anti-inflammatory, immunomodulatory and anti-emetic effects. Recovery time after thyroid surgery may depend on several factors, such as postoperative pain, nausea and vomiting, postoperative sore throat, voice disorders and symptomatic hypocalcaemia (low serum calcium level). However, there is little information in the literature about …

anesthesia
nausea
drainage
oral dexamethasone
parathyroid hormone
  • 0 views
  • 24 Mar, 2022
  • 1 location
MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients (MCLENA-1)

Accumulating evidence indicates that inflammation is prominent both in the blood and central nervous system (CNS) of Alzheimer's disease (AD) patients. These data suggest that systemic inflammation plays a crucial role in the cause and effects of AD neuropathology. Capitalizing on the experience from a previous clinical trial with thalidomide, …

cholinesterase inhibitors
thalidomide
depression
cancer
cholinesterase inhibitor
  • 0 views
  • 30 Apr, 2022
  • 1 location
Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients

This study aims to evaluate the effect of Metformin as add- on therapy for improving the outcome in RRMS patients.

disease or disorder
interferon
brain mri
MRI
diabetes
  • 0 views
  • 18 Jun, 2022
  • 1 location
Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory Pathology

Background The disease leukocyte adhesion deficiency type 1 (LAD1) affects white blood cells. Those are immune system cells. In people with LAD1, white blood cells do not properly communicate with the rest of the body. This causes uncontrolled inflammation, particularly in the gums. People with LAD1 can get frequent infections …

  • 21 views
  • 28 Jun, 2022
  • 1 location
Neuromodulation of Inflammation and Endothelial Function

Heart failure with reduced ejection fraction (HFrEF) is a major cause of mortality in United States. Aging is a major risk factor for adverse outcomes associated with HFrEF, with majority of the patient's over the age of 50, continuing to experience symptoms, reduced exercise capacity and poor quality of life. …

  • 0 views
  • 27 May, 2022
  • 1 location
tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease (tDCS/PES_SCD)

So far, no study investigated the safety and efficacy analgesic of transcranial direct current stimulation (tDCS) associated to peripheral electrical stimulation (PES) in individuals with SCD who suffer from chronic pain. Several studies have reported a decrease in OHb concentration in the regions below the electrodes and in other cortical …

osteonecrosis
analgesics
analgesia
transcranial direct current stimulation
chronic pain
  • 18 views
  • 24 Feb, 2022
  • 1 location
Heart Failure Resilience Intervention for Caregivers (HEROIC)

Heart failure (HF) patients with supportive caregivers have better physical health, emotional health, and quality of life. But caregivers have an increased risk of caregivers' own worsening health and often feel a sense of burden related to caregiving. However, caregivers receive very little support to balance caring for the patient …

heart failure
Accepts healthy volunteers
  • 0 views
  • 30 Jun, 2022
  • 1 location
Interleukin-11 Can Prevent and Treat of Radioactive Oral Mucitis

Radiation induced oral mucositis which may result in reduced quality of life is commonly seen during radiotherapy, especially combined with chemotherapy. This study is a prospective, multicenter, and exploratory study. The aim of this study is to explore predictive factors of acute radiotherapy induced oral mucositis in nasopharyngeal carcinoma patients …

chemotherapy regimen
cancer
mucositis
nasopharyngeal carcinoma
carcinoma
  • 14 views
  • 15 Feb, 2022
  • 1 location
TNFalpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 During TIL Treatment of Advanced Melanoma (TUNINTIL)

This is an open-label, phase 1, first-in-human (FIH), dose-escalation, multicenter, multinational trial evaluating the safety of oncolytic adenovirus TILT-123 as monotherapy and in association with T-cell therapy with TILs in metastatic melanoma patients.

  • 12 views
  • 28 Feb, 2022
  • 2 locations