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Found 63 clinical trials
Inspiratory Muscle Training for Chronic Kidney Disease Patients on Hemodialysis

Chronic Kidney Disease (CKD) is a global public health problem with an increasing prevalence and incidence, poor prognosis, and high costs. It is characterized by changes in the kidney structure and functions for more than three months. It is grouped into several stages, including end-stage kidney disease requiring renal replacement …

  • 24 Mar, 2022
Artery Function Responses to Heat Therapy and Exercise Training

This study will explore the effects of 8 weeks of local leg heat therapy, exercise training, or both on measures of vascular function, cardiorespiratory fitness, and muscle strength in young, healthy individuals. Participants will be allocated into either a control group that will maintain their regular physical activity habits; or …

  • 02 Aug, 2021
  • 1 location
Effect of Protein Hydrolysate Supplement Influencing Systemic Muscle Function Marker Expression Post-resistance Exercise in Men

A randomised placebo controlled, double-blind, 30 Volunteer trial of Elio™ administered 2.4 grams per day in assessing its effects on post-exercise strength recovery and increases in markers associated with muscle injury and exertion.

Accepts healthy volunteers
  • 02 May, 2022
  • 1 location
Connection Between Periodontitis and Exudative Age-related Macular Degeneration (FLAREPARO)

Aqueous flare is increased in different kind of inflammations of eye. This is caused by disruption of blood-aqueous-barrier. The investigators assume that low grade systemic inflammation, such as periodontitis, increase aqueous flare and possibly activates exudative age-related macular degeneration.

Accepts healthy volunteers
  • 28 Feb, 2022
  • 1 location
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury (POD-01)

The overall goal of this research project is to elucidate underlying pathophysiological mechanisms of postoperative delirium (POD) and to specifically validate perioperative predictive factors that will help in indentifying patients at higher risk of developing POD. The main objective is to evaluate whether intraoperative frontal alpha power in unprocessed electroencephalogram …

cerebral injury
intraoperative eeg
cardiopulmonary bypass
  • 06 May, 2022
  • 1 location
Acute Pancreatitis Targets (APT) Study

The severity of acute pancreatitis varies considerably from minor symptoms to multi-organ failure. The pathophysiological mechanisms associated with these individual differences in severity are largely unknown. Acute pancreatitis is therefore classified based on clinical characteristics and routine blood samples. Information about pathophysiology and molecular subtypes of acute pancreatitis is needed …

  • 04 Feb, 2021
  • 1 location
Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis (MAGiC-ART)

Sarcoidosis is a heterogeneous disorder of unknown etiology whose signature lesions are granulomatous inflammatory infiltrates in involved tissues. Tissue commonly affected are lungs, skin, eyes, lymph nodes and the heart. In this latter case, cardiac sarcoidosis (CS) can lead to atrioventricular (AV) blocks, ventricular arrhythmias, heart failure (HF) and sudden …

  • 17 Feb, 2022
  • 2 locations
Exercise-induced Cardiac Adaptions in Rheumatoid Arthritis Patients During Interleukin-6 vs. Tumor Necrosis Factor Antibody Therapy (RABEX)

The present study will investigative the physiological effects of the cytokines interleukin-6 (IL-6) and tumor necrosis factor (TNF) on the adaptive changes to exercise in patients with rheumatoid arthritis. The investigators hypothesize that blockage of IL-6 receptors will decrease the cardiac and metabolic adaptations to exercise training compared to the …

Accepts healthy volunteers
tumor necrosis factor
tumour necrosis
  • 10 Mar, 2022
  • 1 location
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.

Accepts healthy volunteers
  • 22 Oct, 2021
  • 1 location
Total Versus Partial Omentectomy in the Treatment of Gastric Cancer (TOPO)

is to monitoring the blood levels of immunological factors (interleukins, T cell subtypes, etc.) pre-and postoperatively, depending on the type of omentectomy.

cancer chemotherapy
  • 23 Mar, 2022
  • 1 location