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Found 70 clinical trials
Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2

The purpose of this study is to evaluate the interest of maintenance treatment with interleukin-2 by randomizing the patients being not allogeneic transplanted in complete remission after

myeloid leukemia
remission
  • 14 views
  • 07 Nov, 2020
  • 1 location
A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2

The purpose of the study is to compare the efficacy and safety of standard chemotherapy regimen 2HRZE/4HR plus IL-2 and standard regimen 2HRZE/4HR for newly diagnosed smear positive pulmonary tuberculosis.

  • 0 views
  • 04 Mar, 2021
  • 16 locations
Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD)

The main purpose of this study is to see if a drug called aldesleukin, can preserve insulin production in children and young adults recently diagnosed with type 1 diabetes. One group will receive aldesleukin and the other a placebo.

  • 0 views
  • 01 Feb, 2021
  • 6 locations
Bevacizumab and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer

kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Interleukin-2 may stimulate the white blood cells

diabetes
aldesleukin
cervical carcinoma in situ
carcinoma
carcinoma in situ
  • 17 views
  • 07 Nov, 2020
  • 2 locations
Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx

RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells of the mouth or oropharynx. Radiation therapy uses high-energy x-rays to damage tumor cells. It is

interleukin-2
x-rays
oral cancer
tumor cells
immunomodulator
  • 18 views
  • 07 Nov, 2020
  • 1 location
Cell Therapy of Cancer With Allogeneic Blood Lymphocytes Activated With Recombinant Interleukin-2 (rIL-2) for Metastatic Solid Tumors

The present protocol is designed to investigate the potential application of allogeneic cell-mediated immunotherapy in metastatic solid tumors similarly to the well established graft versus leukemia (GVL) effects in patients with hematologic malignancies. Patients with metastatic solid tumors resistant to conventional modalities will be eligible to participate in a treatment …

interferon
solid neoplasm
hematologic malignancy
sarcoma
breast cancer
  • 6 views
  • 07 Nov, 2020
  • 1 location
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Adoptive Cell Therapy Following a Non-myeloablative Lymphodepleting Induction Regimen in Metastatic Melanoma Patients

Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) in combination with lymphodepletion and high-dose interleukin 2 (IL-2) has demonstrated reproducible objective response

  • 10 views
  • 22 Jan, 2021
  • 1 location
Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

accounts for 30-50% of all cases. SCID-X1 is caused by defects in the common cytokine receptor gamma chain, which was originally identified as a component of the high affinity interleukin-2 receptor (IL2RG

  • 3 views
  • 18 Feb, 2021
  • 1 location
Bioequivalence Study of Tacrolimus in Healthy Volunteers

This is an in-vivo study to investigate the bioequivalence of generic tacrolimus and its reference listed drug (RLD). The objective of this study is to investigate the bioequivalence of generic Tacrolimus and RLD in healthy male and non-pregnant, non-lactating female volunteers under fasting conditions. The outcome of this study will …

  • 0 views
  • 24 Mar, 2021
  • 1 location