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Found 9 clinical trials
Featured trial
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3

  • 6 views
  • 11 Aug, 2022
  • 5 locations
A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder

The proposed project will pilot the use of IGF-1 as a novel treatment for core symptoms of autism. We will use a double-blind, placebo-controlled crossover trial design in five children with autism to evaluate the impact of IGF-1 treatment on autism-specific impairments in socialization, language, and repetitive behaviors. We expect …

autism
pervasive developmental disorder
  • 489 views
  • 04 Oct, 2022
  • 1 location
Gene Expression Changes In Young and Geriatric Skin

young adult and geriatric skin is that young skin has a lot of a protein called insulin-like growth factor-1 (IGF-1), whereas geriatric skin has very little. The current study will test how young adult

insulin
Accepts healthy volunteers
cancer
  • 32 views
  • 07 Apr, 2022
  • 1 location
Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study (CABATEN)

growth factor (VEGF), platelet-derived growth factor (PDGF), insulin-like growth factor 1 (IGF-1), basic fibroblast growth factor (BFGF), and transforming growth factor (TGF)-α and -β. The (over

metastatic disease
biological therapy
carcinoid
neuroendocrine tumor
adrenaline
  • 0 views
  • 24 Mar, 2022
  • 14 locations
Lifestyles Of Health And Sustainability for Breast Cancer Survivors

The purpose of this study is to examine the effects of exercise program on health-related physical fitness and biomarkers among breast cancer survivors.

adjuvant chemotherapy
immunostimulant
lumpectomy
mastectomy
  • 1 views
  • 15 Apr, 2021
  • 1 location
Lifestyle Physical Activity and Cognitive Training Interventions: Preventing Memory Loss in Older Women With Cardiovascular Disease (MindMoves)

Older women with cardiovascular disease (CVD) are at greater risk for memory loss, an important public health issue due to the negative effects to quality of life and health care costs. This research will be the first to examine the independent and combined effects of a lifestyle physical activity intervention …

Accepts healthy volunteers
hypertension
  • 0 views
  • 23 Mar, 2022
  • 1 location
Investigating the Effectiveness of Vibration Therapy on Sarcopenia in Osteoarthritis Knee Patients

Osteoarthritis (OA) is one of the commonest chronic degenerative conditions affecting our aging population. It limits joint movement and causing disability in elderlies due to discordant symptoms such as pain and stiffness. The prevalence of radiologic knee osteoarthritis increases in proportion to age, reaching an astounding 64.1% for patients whom …

osteoarthritis
stiffness
  • 29 views
  • 08 Apr, 2022
  • 1 location
Developing a Simple Recognition System of Acromegaly

We will compare the features of 3D stereophotography of acromegaly patients with that of healthy people. We hope to develop a computerized model to help screening acromegaly patients for early detection and treatment.

  • 46 views
  • 21 Jan, 2021
Atrial Fibrillation in Relationship to Plasma Biomarkers

The general objective of this study is to: To identify novel plasmatic biomarkers associated with prevalent/incident atrial fibrillation in patients with high risk for AF and stroke. To assess predictive ability of novel plasmatic biomarkers (especially apelin and miRNAs) on prevalent/incident atrial fibrillation in patients with high risk for AF …

  • 0 views
  • 27 Jan, 2021
  • 6 locations