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Found 51 clinical trials
Featured trial
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3

  • 20 May, 2022
  • 3 locations
A Safety, Tolerability and Efficacy Study of VRDN 001 in Healthy Volunteers and Persons With Thyroid Eye Disease (TED)

The investigational drug, VRDN-001, is a monoclonal antibody that inhibits the activity of a cell surface receptor called insulin-like growth factor-1 receptor (IGF-1R). Inhibition of IGF-1R may

Accepts healthy volunteers
  • 08 Mar, 2022
  • 1 location
Bone Graft Cultivation by Periosteal Elevation

growth factor-2(FGF2), Transforming Growth Factor(TGFB1), and Insulin-like growth factor(IGF1)) assessment will be done as well

  • 11 Apr, 2022
Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients (ProBoNo)

and densitiy of the hamstrings assessed by ultrasound and histology, the process of gastric residual volume, number of diarrhoea events and laboratory findings like glucose, urea and insulin like

Accepts healthy volunteers
  • 05 Mar, 2022
  • 1 location
Achilles Tendinopathy Shear Wave Elastography Study

The purpose of this prospective study is to utilize a real-time ultrasound modality known as real-time Shear Wave Elastography (SWE) to first study the viscoelastic properties of the Achilles tendon to understand the functional differences between normal/asymptomatic vs tendinotic/symptomatic tendon states. The secondary aim will be to assess the degree …

  • 27 Feb, 2022
  • 1 location
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)

Greater Trochanteric Pain Syndrome (GTPS), also known as Trochanteric Bursitis, is a painful condition predominantly affecting middle aged women. It is characterised by pain in the lateral hip exacerbated by movement and lying on the affected side. GTPS encompasses different conditions including gluteus medius/minimus tendinopathy and bursal inflammation. The treatment …

  • 01 Mar, 2022
  • 1 location
ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer

ABCSG C08 is a randomized, two-arm, multicenter trial to investigate the efficacy of endurance exercise following adjuvant chemotherapy in patients with colorectal cancer. Indication: Locally advanced colorectal cancer after adjuvant chemotherapy. Evidence supporting the beneficial effects of exercise programs during chemotherapy are available, the results across studies are not entirely …

adenocarcinoma of colon
adjuvant chemotherapy
  • 01 May, 2021
  • 9 locations
Biomarker-guided Intervention to Prevent Acute Kidney Injury

There is no specific therapy for acute kidney injury. It is presumed that supportive measures improve the care and outcome of patients with acute kidney injury. The investigators hypothesize that the implementation of a bundle of supportive measures adapted to patients undergoing major non-cardiac surgery reduces the occurrence of AKI. …

  • 28 Dec, 2021
  • 7 locations
The Bangladesh Environmental Enteric Dysfunction Study (BEED)

This is a community-based intervention study which will be undertaken at Mirpur, Dhaka, Bangladesh. Participants will be recruited from two age groups: a child cohort (age 12 to 18 months) and an adult cohort (age 18 to 45 years). The child cohort will consist of stunted children (length for age …

trace elements
body mass index
nutrition education
  • 25 Mar, 2022
  • 1 location
Chinese Medicine WT for Spinocerebellar Ataxia Type 3

effective treatment or palliative methods for patients in the present days. However, low-dose growth hormone, or its downstream product, insulin-like growth factor I (IGF-1), may deter the progress of SCA3

  • 01 Nov, 2021
  • 1 location