Found 198 clinical trials
mTOR as Mediator of Insulin Sensitivity Study
The study investigates the role of mTOR in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. This will be investigated in young healthy male
- 0 views
- 11 Jul, 2022
- 1 location
Effect of Dietary SFA and Fructose on Hepatic Insulin Sensitivity
this end, 18 overweight/obese, but otherwise healthy, males and females will take part in the randomized dietary interventions. The primary outcome is hepatic insulin sensitivity (suppression of EGP
- 0 views
- 05 Apr, 2023
- 1 location
Colonic Delivery of Butyrate to Improve Insulin Sensitivity and Lower Triglycerides in Type 1 Diabetes Subjects
The investigators are interested to evaluate the effect of BKR-017 (colon-targeted 500 mg butyrate tablets) as adjuvant therapy on metabolic control in type 1 diabetes (TID) subjects.
- 0 views
- 21 Oct, 2022
- 1 location
Novel Approaches to Enhance Insulin-sensitizing Effects of Exercise: Targeting PAHSA Metabolism (ETAPA)
regarding the important role of PAHSA lipokinins in exercise-induced enhancement of insulin sensitivity and the identification of potential drug targets that could be used to further improve PAHSA
- 0 views
- 25 Oct, 2022
- 1 location
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism (Glucagon)
insulin/glucose to test for insulin sensitivity. Clinical Relevance: The results of this study will help the study team to further understand the pathophysiology of metabolic disturbances that is
- 3 views
- 07 Oct, 2022
- 2 locations
Evaluating the Metabolic Effects of Dietary NItrate Supplementation for Improving Skeletal Muscle Mitochondrial Function, Insulin Sensitivity, Insulin Secretion, Body Fat Composition and Overall Health (NIMMI)
Dietary nitrate is found to enhance muscle fatty acid oxidation/glucose uptake and increase mitochondrial biogenesis, which in turn, aid in the prevention and management of metabolic diseases. In recent years, inorganic nitrate supplementation is clinically emerging as a therapeutic strategy for possible treatment and management of metabolic diseases and cardiometabolic …
- 0 views
- 21 Oct, 2022
- 1 location
Effect of Gender Affirming Hormone Therapy on Glucose Metabolism
The study will test: whether estrogen treatment in transwomen is associated with improved insulin sensitivity and beta cell function whether testosterone treatment in
- 24 views
- 23 Mar, 2022
- 1 location
Acute Response to Exercise in Patients With Rheumatoid Arthritis
biological IL-6 blocking agents and exercise on metabolic responses, such as insulin sensitivity and glucose uptake, in patients with RA. To answer this question, adult women diagnosed with RA and healthy
- 0 views
- 04 Sep, 2021
- 1 location
Comparison of Meal-Time Dosing of Insulin in Cystic Fibrosis Related Diabetes
doses, body weight, and insulin sensitivity along with predisposition to hypoglycemia. Bolus insulin dosing is an important part of CFRD management due to the high nutritional demands of these patients
- 13 views
- 07 Oct, 2022
- 1 location
Acute Effects of High Intensity Training in Pregnancy on Fetal Well-being and Blood Flow Distribution (HITFLOW)
improvements in insulin sensitivity and fitness compared with continuous moderate intensity training in individuals at increased risk for cardiometabolic diseases. Even short-term (6 weeks) HIT with brief (15
- 0 views
- 04 Apr, 2023
- 1 location