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Found 1234 clinical trials
Featured trial
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3

  • 6 views
  • 11 Aug, 2022
  • 5 locations
Featured trial
Effects of Almonds on Glycemia in Adults With Elevated Hemoglobin A1c Concentrations

This study will examine the effects of regular almond consumption by individuals with elevated HbA1c on long-term glycemic control.

Accepts healthy volunteers
  • 15 views
  • 15 Jun, 2022
  • 1 location
Featured trial
Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) (Biotics_RTT)

The study will examine the potential efficacy and safety of two pre- and post-biotics on markers for gut inflammation and intestinal microbiota ecology in patients with Rett syndrome. Moreover, this trial will search for possible effects on epileptogenesis and quality of life.

seizure
  • 0 views
  • 11 Jul, 2022
  • 1 location
Featured trial
Type 2 Diabetes Study – Seeking Volunteers Who Treat with Any Combination of Medications, Except Insulin.

, Bydureon, Victoza, Trulicity, Tanzeum, Ozempic, or Rybelsus-[oral].)  This is a study of an investigational once weekly basal insulin, that may help improve

  • 136 views
  • 08 Oct, 2021
  • 1 location
Featured trial
A 52-week study comparing the efficacy and safety of once weekly IcoSema and once weekly insulin Icodec, both treatment arms with or without oral anti-diabetic drugs, in participants with type 2 diabetes inadequately controlled with daily basal insulin. COMBINE 1

Objective: To confirm superiority of once weekly IcoSema compared with once weekly insulin Icodec, both treatment arms with or without OADs, in terms of glycaemic control measured by change in

  • 0 views
  • 29 Sep, 2022
  • 1 location
Featured trial
  • 0 views
  • 28 Sep, 2022
  • 1 location
Featured trial
  • 0 views
  • 13 Sep, 2022
  • 1 location
Featured trial
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative

Background: Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. Another disorder, atherosclerosis, is a process in which cholesterol …

diabetes
atherosclerosis
heart disease
cholesterol measurement
  • 123 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Inflammatory Characterization of Known or Possible Cardiovascular Diseases

Background: Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …

diabetes
heart disease
fats
  • 167 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Type 2 Diabetes - On Insulin

Type 2 Diabetes - On Insulin

  • 244 views
  • 23 Nov, 2020
  • 1 location