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Found 20 clinical trials
A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients

This study will explore 2 different doses of inotuzumab ozogamicin including the dose that is approved and a lower dose. The main purpose of this study is to evaluate whether a dose of

lymphoma
cancer
blast cells
inotuzumab
kinase inhibitor
  • 178 views
  • 24 Jul, 2021
  • 80 locations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL Mixed Phenotype Acute Leukemia and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This

prednisone
lymphoma
dexamethasone
monoclonal antibodies
methotrexate
  • 42 views
  • 31 Jul, 2021
  • 114 locations
A Treatment Study Protocol for Participants 1-45 Years With Acute Lymphoblastic Leukaemia

ALLTogether collects the experience of previously successful treatment of children and young adults, with ALL from a number of well-renowned study groups into a new master protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several randomised …

doxorubicin
imatinib
dexamethasone
vincristine
inotuzumab
  • 27 views
  • 27 Jan, 2021
  • 102 locations
Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely be given to

leukemia
autologous hematopoietic stem cell transplant
platelet count
cell transplantation
remission
  • 0 views
  • 26 Jul, 2021
  • 6 locations
Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

This trial is a limited multi-center, Phase II study to evaluate inotuzumab ozogamicin (Besponsa) in pediatric patients with MRD positive CD22-positive B-lymphoblastic leukemia (B-ALL

left ventricular fractional shortening
cytarabine
conjugated bilirubin
b-cell acute lymphoblastic leukemia
remission
  • 10 views
  • 02 Jul, 2021
  • 1 location
Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

This phase II trial studies how well inotuzumab ozogamicin works in treating patients with B-cell acute lymphocytic leukemia with positive minimal residual disease. Inotuzumab ozogamicin is a

lymphoid leukemia
remission
residual tumor
monoclonal antibodies
kinase inhibitor
  • 15 views
  • 19 Mar, 2021
  • 2 locations
Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

This research study will add an anti-cancer drug (called inotuzumab ozogamicin also known as "InO") to treatment for participants with newly diagnosed Philadelphia chromosome-positive (Ph

  • 0 views
  • 20 May, 2021
  • 1 location
Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

This is a multi-center, phase 2A exploratory study of feasibility and effectiveness of Inotuzumab Ozagomicin in adult patients with Acute Lymphoid Leukemia (ALL) with positive minimal residual

cell transplantation
b-cell acute lymphoblastic leukemia
residual tumor
lymphoid leukemia
inotuzumab
  • 0 views
  • 25 Jan, 2021
  • 18 locations
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

This partially randomized phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with newly diagnosed

dexamethasone
imatinib
platelet count
absolute neutrophil count
steroid therapy
  • 45 views
  • 29 Jul, 2021
  • 473 locations
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

This phase I trial studies the best dose of inotuzumab ozogamicin in combination with chemotherapy in treating patients with B-cell acute lymphoblastic leukemia that has come back (recurrent) or

  • 0 views
  • 25 May, 2021
  • 1 location