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Found 17 clinical trials
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This

monoclonal antibodies
pegaspargase
lymphoblastic lymphoma
cytarabine
methotrexate
  • 56 views
  • 27 May, 2022
  • 116 locations
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

ALLTogether collects the experience of previously successful treatment of infants, children and young adults, with ALL from a number of well-renowned study groups into a new master protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several …

imatinib
doxorubicin
inotuzumab
dexamethasone
vincristine
  • 70 views
  • 23 Mar, 2022
  • 49 locations
Venetoclax Plus Inotuzumab for B-ALL

This research study is evaluating the safety and efficacy of administering venetoclax and inotuzumab ozogamicin in combination in patients with acute lymphoblastic leukemia (ALL) The

venetoclax
inotuzumab ozogamicin
graft versus host disease
leukemia
lymphocytic leukemia
  • 1 views
  • 27 Oct, 2021
  • 2 locations
Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely be given to

cell transplantation
b-cell lymphoma
tyrosine
remission
platelet count
  • 0 views
  • 24 Feb, 2022
  • 4 locations
Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

This trial is a limited multi-center, Phase II study to evaluate inotuzumab ozogamicin (Besponsa) in pediatric patients with MRD positive CD22-positive B-lymphoblastic leukemia (B-ALL

blinatumomab
lymphoid leukemia
graft versus host disease
prednisolone
b-cell acute lymphoblastic leukemia
  • 10 views
  • 13 May, 2022
  • 1 location
Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

This phase II trial studies how well inotuzumab ozogamicin works in treating patients with B-cell acute lymphocytic leukemia with positive minimal residual disease. Inotuzumab ozogamicin is a

monoclonal antibodies
monoclonal protein
tyrosine kinase inhibitor
stem cell transplantation
leukemia
  • 15 views
  • 21 Mar, 2022
  • 1 location
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

This phase I trial studies the best dose of inotuzumab ozogamicin in combination with chemotherapy in treating patients with B-cell acute lymphoblastic leukemia that has come back (recurrent) or

  • 0 views
  • 20 Feb, 2022
  • 1 location
Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Acute Lymphoblastic Leukemia

This phase I/II trial studies the side effects and best dose of inotuzumab ozogamicin and to see how well it works when given together with combination chemotherapy in treating older patients

rituximab
monoclonal antibodies
anthracyclines
cytarabine
methotrexate
  • 38 views
  • 26 Mar, 2022
  • 1 location
Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia (ALL2418)

This is a multi-center, phase 2A exploratory study of feasibility and effectiveness of Inotuzumab Ozagomicin in adult patients with Acute Lymphoid Leukemia (ALL) with positive minimal residual

cell transplantation
minimal residual disease
lymphoid leukemia
inotuzumab
b-cell acute lymphoblastic leukemia
  • 0 views
  • 25 Mar, 2022
  • 28 locations
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

The goal of this phase II clinical study is to learn about the safety of inotuzumab ozogamicin when given with fludarabine, with or without bendamustine, melphalan, and rituximab before and

rituximab
hla-a
fludarabine
monoclonal antibodies
allogeneic bone marrow transplantation
  • 2 views
  • 21 Apr, 2022
  • 1 location