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Found 17 clinical trials
Making PrEP Smart: An HIV Testing and PrEP Electronic Support Tool ("SmartPrEP" App) for Women on PrEP

Primary Objective: To assess PrEP adherence among sexually-active and/or injection-drug using, HIV-negative cis- and transgender women who use the "SmartPrEP" phone app to support PrEP adherence

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
Determining the Feasibility of Outpatient Parenteral Antibiotic Therapy for Persons Who Inject Opioids

Patients with a history of injection drug use are historically excluded from home outpatient parenteral antibiotic therapy programs. Recent small pilot programs have demonstrated that these

  • 11 views
  • 20 Apr, 2022
  • 1 location
The Kentucky Viral Hepatitis Treatment Study (KeY Treat)

The overarching goal of the Kentucky Viral Hepatitis Treatment Project (KeY Treat) is to increase hepatitis C virus (HCV) treatment access and delivery in a rural Appalachian community, which is in the midst of the opioid/hepatitis C (HCV) syndemic. KeY Treat is a clinical research study seeking to determine whether …

sofosbuvir
epclusa
sofosbuvir/velpatasvir
velpatasvir
antiviral drugs
  • 13 views
  • 24 Feb, 2022
  • 1 location
Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia

This pragmatic, multisite, implementation and effectiveness research evaluates a strategy to improve HIV treatment outcomes (increased rates of patients on ART with virological suppression, improved treatment retention and ART adherence) for people living with HIV (PLWH) with opioid use disorder (OUD). Engaging 4 large regional HIV/AIDS treatment centers in Malaysia, …

AIDS
  • 0 views
  • 28 Jun, 2022
  • 1 location
Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs (TEMPO)

This project aims to evaluate two strategies of Hepatitis C virus (HCV) testing compared to standard of care among people who inject drugs at needle and syringe program (NSP) services in Australia, to see if it can improve the number of people who start treatment following an HCV diagnosis: HCV …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services (CoMPASS)

The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exposure prophylaxis (PrEP) adherence and support services (CoMPASS) to promote HIV prevention among individuals with opioid use disorder who inject drugs. In parallel, the investigators will …

Accepts healthy volunteers
  • 0 views
  • 11 May, 2022
  • 4 locations
Couples ART Adherence Intervention for PWID in Kazakhstan

The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression. The

violence
behavioral therapy
AIDS
Accepts healthy volunteers
drug use
  • 13 views
  • 09 Feb, 2022
  • 1 location
Pharmacist-led Hepatitis C Management (PHARM-C)

those with a history of past or current injection drug use. Despite these advances in diagnostic streamlining and increased cure rates, engagement post-diagnosis continues to be a major gap. Although

  • 0 views
  • 14 May, 2022
  • 1 location
Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults

This randomized controlled trial (RCT) will test the efficacy of a Community Health Worker/Registered Nurse (CHW-RN) HCV intervention for homeless individuals, many who are also drug users. The intervention will be designed during Phase I of the proposal using an iterative process between a Community Advisory Board (CAB) and focus …

  • 0 views
  • 06 Jun, 2022
  • 7 locations
Partial Oral Antimicrobials to Treat Infective Endocarditis in People Who Inject Drugs

Infective endocarditis (IE) is a serious infection associated with significant morbidity and mortality. Recent studies demonstrated an increased risk of infective endocarditis in people who inject drugs (PWIDs). PWIDs have a high rate of non-compliance with hospital admissions and leaving against medical advice. A recent landmark randomized controlled trial demonstrated …

  • 0 views
  • 17 Jun, 2021
  • 2 locations