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Found 7 clinical trials
Defining the Severe Paediatric Asthma Endotype

The primary objective of this project is to extensively characterize the endotypes of pre-schoolers (0 to 6 years) and school-age children (6 to 12 years) with SA using an integrated approach, combining a description of their phenotype (asthma symptoms, atopy, and lung function) associated with histological (airway inflammation and remodelling), …

  • 0 views
  • 29 Nov, 2021
  • 1 location
Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients

inhaled steroids is used in various pathologies such as Asthma and Chronic Obstructive Pulmonary Disease (COPD) to reduce the airway inflammatory response. The advantage of using inhaled corticosteroids

  • 1 views
  • 17 Feb, 2021
  • 2 locations
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Many studies have investigated the efficacy and safety of Intravenous magnesium sulfate and inhaled steroids in addition to the standard treatment for patients with severe asthma attacks.

budesonide
asthma attack
inhaled steroids
  • 0 views
  • 04 Oct, 2022
  • 1 location
Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes (SANDIA)

Patients with obese late onset (after childhood) asthma can have lower FeNO levels, yet be highly symptomatic and poorly responsive to inhaled steroids. This is a common asthma phenotype

Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location
Intra-tracheal Instillation of Budesonide to Prevent Chronic Lung Disease (STOPCLD)

Preterm infants are randomized to received either Intra-tracheal instillation of budesonide using surfactant as vehicle or a placebo. Intra-tracheal instillation of budesonide using surfactant as vehicle would facilitate its delivery to the periphery of the lung and would inhibit lung inflammation and mitigate acute lung injury.

budesonide
mechanical ventilation
FIO2
acute lung injury
  • 0 views
  • 14 May, 2022
  • 1 location
Comparing TAP Blocks Bupivacaine, and Placebo for Plane (CLEVELAND)

The study will prospectively compare the analgesic efficacy of TAP blocks with liposomal bupivacaine, plain bupivacaine, and placebo in patients who are scheduled for major abdominal surgery. The primary aim is to assess the duration of the local analgesia (determined by pinprick and cold) in all four quadrants. Comparing opioid …

  • 0 views
  • 15 Mar, 2022
  • 1 location
Clinic Navigation and Home Visits to Improve Guideline-based Care and Outcomes in Low Income Minority Adults With Asthma (HAP3)

Asthma-related deaths are more numerous among low-income minority patients and older adults with chronic diseases. Guidelines for asthma management have not addressed the needs of these groups. The investigators recently demonstrated the feasibility, acceptability, and evidence of effectiveness of two interventions to improve access to care, patient-provider communication, and asthma …

pulmonary disease
corticosteroids
Accepts healthy volunteers
COPD
obstructive lung disease
  • 3 views
  • 07 Oct, 2022
  • 2 locations