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Found 70 clinical trials
Examination of Radiographic Progression Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

and physiotherapy which are oft insufficient. Treatment with the TNF-alpha blocking agent infliximab was shown to have definite clinical efficacy in patients with active AS on a short- and a

NSAID
anti-tumor necrosis factor therapy
infliximab
tumor necrosis factor alpha
steroidal anti-inflammatory drugs
  • 51 views
  • 07 Nov, 2020
  • 8 locations
Topical Infliximab for Sterile Corneal Melt

necrolysis or mucous membrane pemphigoid. Infliximab is an antibody against tumour necrosis factor alpha and has been used to treat or prevent corneal melt in certain patients with inflammatory of

  • 8 views
  • 03 Feb, 2021
  • 2 locations
Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis

The purpose of this study is to establish whether RA patients with moderate to severe disease activity with unsustainable response to infliximab 3 mg/kg every 8 weeks have better efficacy

adalimumab
infliximab
  • 35 views
  • 07 Nov, 2020
  • 5 locations
Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS)

This study will evaluate the Efficacy and Safety of Infliximab versus Cyclophosphamide in Subjects with Idiopathic Refractory Scleritis. The term scleritis describes a chronic

  • 0 views
  • 24 Jan, 2021
  • 1 location
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

rheumatoid arthritis. Etanercept is a fusion protein with TNF receptor type II p75 and IgG1 Fc fragment, whereas adalimumab, infliximab, and golimumab are monoclonal antibodies. Certolizumab is a fusion

NSAID
DMARD
enthesitis
monoclonal antibodies
rheumatoid arthritis
  • 17 views
  • 04 Aug, 2021
  • 35 locations
Randomised Evaluation of COVID-19 Therapy

), Convalescent plasma, Synthetic neutralizing antibodies (REGN-COV2), Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin or Anakinra (children only) prevents death in patients with COVID-19.

ritonavir
pneumonia
hydroxychloroquine
lopinavir
covid-19
  • 0 views
  • 05 Aug, 2021
  • 3 locations
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

This trial studies the role of the gut microbiome and effectiveness of a fecal transplant on medication-induced gastrointestinal (GI) complications in patients with melanoma or genitourinary cancer. The gut microbiome (the bacteria and microorganisms that live in the digestive system) may affect whether or not someone develops colitis (inflammation of …

  • 0 views
  • 11 Apr, 2021
  • 1 location
Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms

Patients harboring dolichoectactic vertebrobasilar (DVB) aneurysms are at risk of suffering SAH, ischemic stroke, and/or brainstem compression and many patients are not offered invasive treatment due to the futility of existing surgical methods. Consequently, there is demand for development of medical therapy for DVB aneurysms

stroke
invasive treatment
ischemic stroke
aneurysm
  • 2 views
  • 23 Jan, 2021
  • 1 location
Infliximab for Treatment of Ipilimumab Colitis

This research study is evaluating the effectiveness and safety of infliximab therapy compared with steroids in the treatment of ipilimumab-induced colitis in patients with III/IV melanoma.

metastasis
infliximab
prednisolone
pd-l1
hepatitis b surface antigen
  • 0 views
  • 26 Jan, 2021
Optimising Infliximab Induction Therapy for Acute Severe Ulcerative Colitis

The purpose of this study is to identify whether an Accelerated or Intensified Infliximab induction regimen is superior to Standard induction in Acute Severe Ulcerative Colitis in an open label

infliximab
  • 8 views
  • 01 Aug, 2021
  • 1 location