Found 57 clinical trials
Topical Infliximab for Sterile Corneal Melt
necrolysis or mucous membrane pemphigoid. Infliximab is an antibody against tumour necrosis factor alpha and has been used to treat or prevent corneal melt in certain patients with inflammatory of
- 11 views
- 24 Feb, 2022
- 1 location
Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind Multi-centre Trial (RAPID-I) (RAPID-I)
This study evaluates the effectiveness and safety of infliximab in the treatment of acute pancreatitis in adults. A third of participants will receive one single dose of infliximab via infusion
- 7 views
- 11 Mar, 2022
- 1 location
CT to Assess the Efficacy and Safety of Adding GMA to Infliximab in Paediatric Patients With Steroid-refractory Ulcerative Colitis
The primary endpoint will be evaluated through the following variables: PUCAI score, IFX levels, and steroid treatment. Clinical response to IFX will be evaluated through the PUCAI score. The response will be considered clinically significant if PUCAI points continue maintained below 30 during the study period. The IFX response will …
- 0 views
- 09 Jul, 2022
- 7 locations
Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis (ROC-SPA)
rheumatoid arthritis. Etanercept is a fusion protein with TNF receptor type II p75 and IgG1 Fc fragment, whereas adalimumab, infliximab, and golimumab are monoclonal antibodies. Certolizumab is a fusion
- 17 views
- 28 Oct, 2022
- 13 locations
Randomised Evaluation of COVID-19 Therapy (RECOVERY)
), Convalescent plasma, Casirivimab+Imdevimab, Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin, Sotrovimab, Molnupiravir, Paxlovid or Anakinra (children only) prevents death in patients with COVID-19
- 0 views
- 19 Apr, 2022
- 6 locations
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial (CATCO)
This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization.
- 1533 views
- 04 Oct, 2022
- 45 locations
Pembrolizumab + Infliximab for Metastatic Melanoma
The purpose of this research is to test the safety and effectiveness of the investigational combination of pembrolizumab and infliximab in treating metastatic melanoma.
- 0 views
- 20 Apr, 2022
- 1 location
Intravitreal Infliximab for Proliferative Vitreoretinopathy
in cellular morphologies that lead to the formation of fibroblastic cells. Infliximab (Remicade; Janssen Biotech, Horsham, PA, USA) is a mouse-human chimeric antibody that neutralizes the
- 0 views
- 17 Dec, 2021
- 1 location
Infliximab for Treatment of Ipilimumab Colitis
This research study is evaluating the effectiveness and safety of infliximab therapy compared with steroids in the treatment of ipilimumab-induced colitis in patients with III/IV melanoma.
- 10 views
- 06 Nov, 2021
Top Down Versus Step up in Pediatric Ulcerative Colitis
be randomly divided into infliximab (IFX) treatment group (Top down group, TD) and corticosteroids (CS) treatment group (Step-up group, SU). Mucosal healing rate at week 12 will be compared between
- 0 views
- 15 Mar, 2022
- 1 location