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Found 370 clinical trials
Outcomes of Ablation of Unresectable Pancreatic Cancer Using the NanoKnife Irreversible Electroporation (IRE) System

The purpose of this study is to evaluate the short and intermediate term outcomes of the NanoKnife Irreversible Electroporation System when used to treat unresectable pancreatic cancer. In addition, the study will evaluate the efficacy of this device in treating symptoms of unresectable pancreatic cancer. The NanoKnife, System has been …

cancer
obstruction
  • 26 views
  • 08 Apr, 2022
  • 1 location
Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise

A randomised placebo controlled, double-blind, 30 Volunteer trial of Elio™ administered 2.4 grams per day in assessing its effects on post-exercise strength recovery and increases in markers associated with muscle injury and exertion.

Accepts healthy volunteers
  • 1 views
  • 11 Jul, 2022
  • 1 location
ARNI in Asymptomatic Patients With Elevated Natriuretic Peptide and Elevated Left Atrial Volume Index eLEvation

The purpose of this study is to determine whether LCZ696 (valsartan/sacubitril) is safe and has beneficial effects on the heart and blood vessels in patients with high blood pressure and/or diabetes or other risk factors for developing heart failure (elevated levels of natriuretic peptide and elevated left atrial volume index). …

hypertension
sacubitril
natriuretic peptide
diabetes
heart failure
  • 6 views
  • 08 Nov, 2020
  • 1 location
Prebiotic Therapy to Improve Outcomes of Renal Transplant

An investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients undergoing a kidney transplant. Participants will be treated with human milk oligosaccharide (HMO) prebiotic versus placebo over 12 weeks from start of the investigational medication date (approximately 3 months) to test whether HMO …

  • 0 views
  • 26 Apr, 2022
  • 1 location
Acute Pancreatitis Targets (APT) Study (APT)

The severity of acute pancreatitis varies considerably from minor symptoms to multi-organ failure. The pathophysiological mechanisms associated with these individual differences in severity are largely unknown. Acute pancreatitis is therefore classified based on clinical characteristics and routine blood samples. Information about pathophysiology and molecular subtypes of acute pancreatitis is needed …

Accepts healthy volunteers
  • 0 views
  • 10 Aug, 2022
  • 1 location
Sterile Amniotic Fluid Filtrate Epidural Injection.

There is a large population of patients with lumbosacral radicular pain due to spinal stenosis who do not respond to physical therapy or oral medication management, yet wish to avoid spinal surgery or are simply not candidates due to medical co-morbidity. Given the natural history of lumbar spinal stenosis, these …

  • 31 views
  • 06 Jan, 2022
  • 1 location
Radiofrequency Perineural Injection Idiopathic Carpal Tunnel Syndrome

Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into three equal groups using randomized closed envelop method into three groups. Control Group …

conservative management
tingling sensation
nerve conduction velocity
bupivacaine
ultrasound guidance
  • 1 views
  • 06 Oct, 2021
  • 1 location
Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

and inflammatory response, improving analgesic efficacy and sleep quality, and reducing delirium incidence.

anesthesia
analgesics
metastasis
dexmedetomidine
delirium
  • 8 views
  • 30 Apr, 2022
  • 1 location
RESOLUTION: A Double-blind, Randomized, Placebo-controlled, Phase II/III Study of the Efficacy and Safety of LAU-7b in the Treatment of Adult Hospitalized Patients With COVID-19 Disease (RESOLUTION)

A randomized, double-blind, placebo-controlled Phase 2/3 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk of complications.

  • 32 views
  • 16 Sep, 2022
  • 16 locations
Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery

This international, multicentre, pragmatic, double-blind, placebo-controlled, randomised trial of TxA versus placebo will enrol 3,300 patients throughout Australia and internationally. This is an effectiveness trial - some elements of the trial are deliberately left to the perioperative clinicians' discretion in order to reflect usual practice and maximise generalisability.

  • 0 views
  • 28 Jan, 2021
  • 1 location