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Found 26 clinical trials
Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

This randomized phase II trial studies how well carboplatin and paclitaxel with or without panitumumab work in treating patients with invasive triple negative breast cancer. Drugs used in the chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the …

oral contraception
HER2
ejection fraction
edema
carcinoma
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy

This phase II trial studies how well pembrolizumab works in treating patients with stage IV inflammatory breast cancer or triple-negative breast cancer that has spread to other places in the

edema
breast cancer
triple-negative breast cancer
immunohistochemistry
estrogen receptor
  • 32 views
  • 26 Jan, 2021
  • 1 location
Multi-epitope Folate Receptor Alpha Peptide Vaccine GM-CSF and Cyclophosphamide in Treating Patients With Triple Negative Breast Cancer

This randomized phase II trial studies how well multi-epitope folate receptor alpha peptide vaccine, sargramostim (GM-CSF), and cyclophosphamide work to prevent the recurrence of stage 1-3 triple negative breast cancer. Vaccines made from a person's white blood cells mixed with tumor proteins may help the body build an effective immune …

metastatic disease
folate
multi-epitope folate receptor alpha peptide vaccine
sargramostim
carcinoma
  • 23 views
  • 27 Jan, 2021
  • 13 locations
Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer

This research study is studying the usefulness of magnetic resonance imaging (MRI) to screen for brain metastases (spread of the breast cancer to the brain).

HER2
epidermal growth factor
breast cancer
erbb2
recurrent breast cancer
  • 2 views
  • 28 Jan, 2021
Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant Chemotherapy

This phase II trial studies how well atorvastatin works in treating patients with stages IIb-III triple negative breast cancer who did not achieve a pathologic complete response to neoadjuvant chemotherapy. Pathologic complete response is the lack of all signs of cancer in tissue samples removed during surgery after upfront chemotherapy. …

HER2
eosin
carcinoma
breast cancer
erbb2
  • 0 views
  • 25 Jan, 2021
  • 1 location
Three Fraction Radiation to Induce Immuno-Oncologic Response

Patients with high risk breast cancers (any locally advanced breast cancer patient defined as Stages IIB-III [excluding inflammatory breast cancer] with stage IIA being eligible for triple

  • 0 views
  • 25 Jan, 2021
  • 1 location
Neoadjuvant Treatment of Triple Negative Breast Cancer Patients With Docetaxel and Carboplatin to Assess Anti-tumor Activity

study (excluded participants from BCM will include male participants or participants with inflammatory breast cancer). The investigators will pool participants and data from the BCM study and the study

HER2
carboplatin
direct bilirubin
breast cancer
erbb2
  • 0 views
  • 27 Jan, 2021
  • 1 location
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Phase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Pre-operative Magnetic Resonance Imaging (MRI) in Young Breast Cancer Patients

Young women with breast cancer have an increased breast tissue density and conventional imaging tests such as mammography and breast ultrasound are less sensitive and specific for detecting breast cancer than in older breast cancer patients. Breast MRI is an emerging tool that has been proven to improve the ability …

hormone therapy
endocrine therapy
invasive breast cancer
magnetic resonance imaging of breast
  • 4 views
  • 07 Nov, 2020
  • 2 locations
Sacituzumab Govitecan In TNBC

This research study is studying to evaluate sacituzumab govitecan for individuals with localized triple negative breast cancer (TNBC) The names of the study drugs involved in this study is: Sacituzumab govitecan (SG) Pembrolizumab (combination therapy with SG)

HER2
invasive breast cancer
breast cancer
metastasis
erbb2
  • 0 views
  • 02 Feb, 2021
  • 2 locations