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Found 882 clinical trials
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Sternal Cerclage (sternal bone closure after open heart surgery)

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

coronary revascularization
revascularisation
acute coronary syndrome
  • 1160 views
  • 05 Feb, 2021
  • 1 location
featured
HPS-4/TIMI 65/ORION-4: A double-blind randomized placebo-controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease

The ORION-4 clinical trial aims to test a new, twice annual cholesterol injectable medication called inclisiran which has no known side effects. Inclisiran is a PCSK9 gene inhibitor that prevents the PCSK9 from circulating and destroying the body's LDL ("bad" cholesterol) receptors which digest LDL. Inclisiran enhances the effects of …

  • 97 views
  • 11 Jun, 2020
  • 1 location
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Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

To determine if BIIBO93 improves functional outcome at Day 90 as measured by modified Rankin Scale (mRS) when compared with placebo in subjects with Large Hemispheric infarction (LHI) &nbsp

  • 18 views
  • 23 Nov, 2020
  • 1 location
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ASTRAL

BIIB093 is an investigational product under development for the treatment and prevention of severe cerebral edema in patients with large hemispheric infarction (LHI) and for the treatment of brain

  • 30 views
  • 11 Jun, 2020
  • 1 location
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Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

participants with Large Hemispheric Infarction (LHI). The secondary objectives are to determine if BIIB093 improves overall survival at Day 90 when compared with placebo, if BIIB093

  • 12 views
  • 12 Aug, 2020
  • 1 location
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The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes (SURPASS-CVOT)

We are currently recruiting participants for a clinical research study to evaluate the effectiveness of an investigational medication in type 2 diabetics who have had cardiovascular events including, but not limited to heart attack, stroke, cardiac stent placement or bypass, etc.

diabetes mellitus
diabetes
type 2 diabetes
type 2 diabetes mellitus
  • 31 views
  • 14 Jan, 2021
  • 1 location
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Multi-center cross-sectional epidemiological study to characterize the prevalence and distribution of lipoprotein(a) levels among patients with established cardiovascular disease

We are seeking participants for a clinical research study to collect blood specimens and clinical data from individuals that have experienced a heart attack, stroke, or symptomatic blockage in the arteries of the lower extremities.

cardiovascular diseases
cardiovascular disease
stroke
cardiovascular system diseases
heart attack
  • 0 views
  • 25 Jan, 2021
  • 1 location
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A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.

A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in

  • 70 views
  • 23 Nov, 2020
  • 1 location
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  • 90 views
  • 23 Nov, 2020
  • 1 location