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Found 429 clinical trials
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FFR Versus Angiography-Guided Strategy for Management of AMI With Multivessel Disease

The aim of the study is to compare clinical outcomes following fractional flow reserve (FFR)-guided versus angiography only guided strategy in treatment of non-infarction related artery (non-IRA) stenosis in patients with acute myocardial infarction (AMI) with multivessel disease Prospective, open-label, randomized, multicenter trial to test the clinical outcomes following FFR-guided …

troponin
stenosis
angiography
stemi
q waves
  • 0 views
  • 27 Sep, 2021
  • 2 locations
None
Testing the Value of Novel Strategy and Its Cost Efficacy in Order to Improve the Poor Outcomes in Cardiogenic Shock

Cardiogenic shock (CGS) affects up to 10% of patients suffering acute coronary syndrome. It has a 30 day mortality of 45-50%. No pharmacological nor intervention/device trials have had any impact on this mortality in the last 20 years. The EURO SHOCK Trial (supported by the European Union Horizons 2020 programme) …

  • 0 views
  • 12 May, 2021
  • 47 locations
None
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2)

ENCHANTED2 is an international, multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to assess different approaches to manage blood pressure (BP) in acute ischemic stroke (AIS) patients who have undergone mechanical thrombectomy (MT). There are two nested substudies evaluating different approaches to secondary prevention in this high-risk stroke population.

  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Improving Door-to-Balloon Time in STEMI

The investigators prospectively determined the impact on median door-to-balloon time of a protocol mandating (1) emergency department physician activation of the catheterization lab and (2) immediate transfer of the patient to an immediately available catheterization lab by an in-house transfer team consisting of an emergency department nurse, a critical care …

stemi
chest pain
  • 11 views
  • 07 Nov, 2020
  • 1 location
None
China Tongxinluo Study for Myocardial Protection in Patients With Acute Myocardial Infarction

To determine the therapeutic effects of Tongxinluo Capsules as compared with placebo in the treatment of patients with acute ST-elevation myocardial infarction (STEMI): (1) Clinical efficacy and safety at 30 days: the incidence of composite endpoints comprising major adverse cardiovascular and cerebrovascular events (MACCE, including cardiovascular death, myocardial re-infarction, emergency …

stroke
chest pain
heart failure
stemi
bundle branch block
  • 0 views
  • 24 Jan, 2021
  • 7 locations
None
Ticagrelor De-escalation Strategy in East Asian Patients With AMI

Ticagrelor as nonthienopyridine, direct-acting P2Y12 receptor antagonist, had significantly greater platelet inhibition, which could reduce ischemic events at acute phase, however, resulting in more incidence of bleedings than pro-drug P2Y12 receptor inhibitor during chronic phase for management of acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI). Also, East Asians …

  • 0 views
  • 23 Feb, 2021
  • 1 location
None
Study of Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients With a Large Infarct Core

with large infarct volume were limited. In this study, the investigators assume that best medical management plus EVT might be superior than best medical management alone for patients who have evidence

  • 0 views
  • 08 May, 2021
  • 1 location
None
Dapsone for Acute Ischemia Stroke Study

anterior territory brain infarct.

infarct
brain infarction
ischemia
ischemic stroke
  • 50 views
  • 08 Nov, 2020
  • 1 location
None
Non-invasive Vagus Nerve Stimulation in Acute Ischemic Stroke

results in less infarct growth in the penumbra and smaller infarct volumes compared with those of patients not treated with nVNS. The study will be a prospective randomized clinical trial with blinded

stroke
thrombectomy
deficit
infarct
probe
  • 0 views
  • 22 Oct, 2021
  • 1 location
None
Polish-Italian-Hungarian RAndomized ThrombEctomy Trial

TIMI thrombus scale ≥ 1 TIMI 3 flow after PCI MBG 3 CMR – infarct size, measurement of left ventricular end-diastolic EDV and end-systolic volumes ESV and ejection fraction (EF) ECHO

coronary artery bypass graft
acute myocardial infarction
cardiac death
percutaneous coronary intervention
cardiac event
  • 20 views
  • 07 Nov, 2020
  • 3 locations