Found 399 clinical trials
Sternal Cerclage (sternal bone closure after open heart surgery)
The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).
- 1160 views
- 05 Feb, 2021
- 1 location
HPS-4/TIMI 65/ORION-4: A double-blind randomized placebo-controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease
The ORION-4 clinical trial aims to test a new, twice annual cholesterol injectable medication called inclisiran which has no known side effects. Inclisiran is a PCSK9 gene inhibitor that prevents the PCSK9 from circulating and destroying the body's LDL ("bad" cholesterol) receptors which digest LDL. Inclisiran enhances the effects of …
- 97 views
- 11 Jun, 2020
- 1 location
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
The primary objective is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives are to determine if BIIB093 improves overall survival at Day 90 when compared with …
- 12 views
- 12 Aug, 2020
- 1 location
The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes (SURPASS-CVOT)
We are currently recruiting participants for a clinical research study to evaluate the effectiveness of an investigational medication in type 2 diabetics who have had cardiovascular events including, but not limited to heart attack, stroke, cardiac stent placement or bypass, etc.
- 31 views
- 17 May, 2021
- 1 location
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
To determine if BIIBO93 improves functional outcome at Day 90 as measured by modified Rankin Scale (mRS) when compared with placebo in subjects with Large Hemispheric infarction (LHI)
- 18 views
- 23 Nov, 2020
- 1 location
ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery
ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery
- 200 views
- 08 Nov, 2020
- 1 location
Multi-center cross-sectional epidemiological study to characterize the prevalence and distribution of lipoprotein(a) levels among patients with established cardiovascular disease
We are seeking participants for a clinical research study to collect blood specimens and clinical data from individuals that have experienced a heart attack, stroke, or symptomatic blockage in the arteries of the lower extremities.
- 0 views
- 17 May, 2021
- 1 location
EX9924-4473: Semaglutide cardiovascular outcomes trial in patients with type 2 diabetes (SOUL)
Oral Semaglutide
- 90 views
- 23 Nov, 2020
- 1 location
A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.
A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.
- 70 views
- 23 Nov, 2020
- 1 location
DECLARE -Dapagliflozin Effect on CardiovascuLAR Events - A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Dapagliflozin 10 mg Once Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischemic Stroke in Patients with Type 2 Diabetes
DECLARE -Dapagliflozin Effect on CardiovascuLAR Events - A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Dapagliflozin 10 mg Once Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischemic Stroke in Patients with Type 2 Diabetes
- 164 views
- 25 Mar, 2021
- 1 location