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Found 374 clinical trials
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Hybrid Coronary Revascularization Trial

The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).

coronary revascularization
acute coronary syndrome
  • 1160 views
  • 07 Nov, 2020
  • 1 location
featured
HPS-4/TIMI 65/ORION-4: A double-blind randomized placebo-controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease

The ORION-4 clinical trial aims to test a new, twice annual cholesterol injectable medication called inclisiran which has no known side effects. Inclisiran is a PCSK9 gene inhibitor that prevents the PCSK9 from circulating and destroying the body's LDL ("bad" cholesterol) receptors which digest LDL. Inclisiran enhances the effects of …

  • 97 views
  • 11 Jun, 2020
  • 1 location
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Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

The primary objective is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives are to determine if BIIB093 improves overall survival at Day 90 when compared with …

  • 12 views
  • 12 Aug, 2020
  • 1 location
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Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

To determine if BIIBO93 improves functional outcome at Day 90 as measured by modified Rankin Scale (mRS) when compared with placebo in subjects with Large Hemispheric infarction (LHI)  

  • 18 views
  • 23 Nov, 2020
  • 1 location
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The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes (SURPASS-CVOT)

We are currently recruiting participants for a clinical research study to evaluate the effectiveness of an investigational medication in type 2 diabetics who have had cardiovascular events including, but not limited to heart attack, stroke, cardiac stent placement or bypass, etc.

type 2 diabetes mellitus
diabetes mellitus
diabetes
type 2 diabetes
  • 31 views
  • 14 Jan, 2021
  • 1 location
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ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery

ALERTS (Angel Med): Implanted device designed to continuously monitor the electrocardiogram signals and detect shifts that could indicate of a blockage of a coronary artery

  • 200 views
  • 08 Nov, 2020
  • 1 location
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Multi-center cross-sectional epidemiological study to characterize the prevalence and distribution of lipoprotein(a) levels among patients with established cardiovascular disease

We are seeking participants for a clinical research study to collect blood specimens and clinical data from individuals that have experienced a heart attack, stroke, or symptomatic blockage in the arteries of the lower extremities.

heart attacks
cardiovascular system diseases
stroke
cardiovascular disease
cardiovascular diseases
  • 0 views
  • 19 Jan, 2021
  • 1 location
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Healthy Volunteers Invited to Donate Blood for Research Study on Increased Risk of Heart Attack and Stroke in Diabetes

Healthy Volunteers Invited to Donate Blood for Research Study on Increased Risk of Heart Attack and Stroke in Diabetes. *An occasional drinker consumes alcoholic drinks no more than 3 days a week and no more than 12 ounces of beer, 5 ounces of wine or 1 “shot” of whisky or …

  • 7 views
  • 23 Nov, 2020
  • 1 location
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  • 90 views
  • 23 Nov, 2020
  • 1 location
featured
A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.

A multinational, randomized, double-blind, placebo controlled trial to evaluate the effect of Ticagrelor 90mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.

  • 70 views
  • 23 Nov, 2020
  • 1 location