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Found 167 clinical trials
Induction Chemotherapy Followed by Concurrent Chemoradiotherapy in Patients With LA-NPC

Nasopharyngeal carcinoma (NPC) is a malignant tumor that originates in nasopharyngeal epithelial cells. It is common in southern China and Southeast Asia, but the incidence rate is low in most parts of the world. According to the World Health Organization survey, 80% of nasopharyngeal carcinomas occur in China, with high …

cancer
chemotherapy regimen
induction chemotherapy
carcinoma
absolute neutrophil count
  • 2 views
  • 12 Feb, 2022
  • 1 location
Phage II Trial of Stathmin as Predictive Biomarker for TPF Induction Chemotherapy in OSCC

To investigate the predictive value of stathmin expression as a predictive biomarker in OSCC patients, who treated with TPF (docetaxel, cisplatin and 5-fluorouracil ) induction chemotherapy

mouth cancer
squamous cell carcinoma
induction chemotherapy
concurrent chemotherapy
dental caries
  • 1 views
  • 24 Feb, 2022
  • 1 location
Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer

This study is designed to test the Safety and efficacy of induction and individualized neoadjuvant chemotherapy based on oxaliplatin combined with fluorouracil for MRF-negative, moderate-risk and initially resectable middle and low rectal cancer.

capecitabine
adenocarcinoma of rectum
adenocarcinoma
total mesorectal excision
fluorouracil
  • 0 views
  • 28 Feb, 2022
  • 1 location
A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients

To confirm the subgroup result from TPF (docetaxel, cisplatin and 5-fluorouracil ) trial (NCT01542931) that cN2 OSCC patients could benefit from TPF induction chemotherapy compared to the

cancer
squamous cell carcinoma
carcinoma of oral cavity
induction chemotherapy
caries
  • 0 views
  • 07 Oct, 2021
  • 1 location
Induction Chemotherapy Combined With Toripalimab in Locoregionally-Advanced Laryngo-Hypopharyngeal Squamous Cell Cancer

This is a non-randomized phase 1, open-labeled clinical study, 1-arm, single center, to observe efficacy and safety of chemotherapy plus PD-L1 antibody Toripalimab every 21 days for 2 cycles as induction regimen in locoregionally-advanced laryngo-hypopharyngeal squamous cell cancer patients.

  • 0 views
  • 24 Jun, 2021
  • 1 location
Induction Chemotherapy and Toripalimab for Larynx Preservation in Resectable Laryngeal/Hypopharyngeal Carcinoma (INSIGHT)

The aim of this study is to define whether combination of induction chemotherapy and PD-1 inhibitor (Toripalimab) improve the rate of larynx preservation, for patients with resectable laryngeal

  • 0 views
  • 23 Mar, 2022
  • 1 location
Toripalimab Based Induction Chemotherapy Followed by De-escalation Protocols in HPV-related OPSCC

infection. So the investigators studied whether toxicities reducing treatment with reduced radiation dose and omitted concurrent chemotherapy after good response to induction chemotherapy would maintain

  • 0 views
  • 11 May, 2021
  • 1 location
Concurrent and Adjuvant PD-1 Blockade Combined With Induction Chemotherapy Plus Radiotherapy in Nasopharyngeal Carcinoma

This is a phase 2, single-arm, multicenter clinical trial, with the purpose to evaluate the therapeutic efficacy and safety of PD-1 Blockade combined with induction chemotherapy and radiotherapy

  • 0 views
  • 27 Jan, 2021
  • 6 locations
Induction Chemotherapy Followed by Standard Therapy in Cervical Cancer With Aortic Lymph Node Spread

The main objective of this study is to determine whether neoadjuvant chemotherapy with Carboplatin and paclitaxel plus standard cisplatin-based chemoradiation with extended fields improves overall survival rates compared to standard therapy alone in women with cervical cancer with paraaortic lymph node involvement. Women in the experimental arm will receive neoadjuvant …

  • 0 views
  • 25 Jan, 2021
Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 Trial

addition of induction chemotherapy to chemoradiotherapy improves efficacy compared with chemoradiotherapy alone is unclear in hypopharyngeal cancer.We tried to observe the clinical treatment efficiency

  • 0 views
  • 24 Jan, 2021
  • 1 location