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Found 61 clinical trials
GUARDIAN (NCT04884802) Sub-study Comparing Etomidate and Propofol

Some patients participating in the underlying GUARDIAN trial (NCT04884802) will be additionally randomized to etomidate vs propofol for anesthetic induction.

  • 0 views
  • 16 Oct, 2022
  • 1 location
Randomized Trial of Sedative Choice for Intubation (RSI)

Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk …

  • 3 views
  • 04 Oct, 2022
  • 10 locations
The Clinical Study of Dexmedetomidine and Esketamine Combined Infusion Undergoing Modified Radical Mastectomy

esketamine (0.5 mg/kg)over 10 min before the induction of anesthesia, and then dexmedetomidine were infused at a rate of 0.4 µg/kg/h and 2 µg/kg/min until 20 min before the end of operation, respectively

Accepts healthy volunteers
  • 0 views
  • 09 May, 2022
  • 1 location
The PREVENT AGITATION Trial II - Children 1 Year

. sedation in the intensive care unit, prevention of withdrawal symptoms after long-term sedation, as premedication before induction of anaesthesia or as treatment/prevention of emergence agitation. The

  • 0 views
  • 20 Nov, 2021
  • 1 location
Opioid Free Anesthesia in Total Hip Arthroplasty (OFATHA)

Total hip arthroplasty (THA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery. Postoperative pain management in THA requires multimodal analgesia, combining drugs and injection of a local anesthetic (LA). But, the best anesthesia strategy …

  • 3 views
  • 26 Mar, 2022
  • 1 location
Dexametomedine Versus Ketamine as an Adjuvant in Ultrasound Guided Erector Spinae Block for Perioperative Thoracotomy Pain Control in Pediatrics Cardiothoracic Surgeries: A Randomized Controlled Trial

A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with thoracotomy incision.

  • 0 views
  • 15 Oct, 2022
  • 1 location
Laryngeal Mask Supreme and I-Gel in Edentulate Geriatric Patients

The primary aim of this study is to evaluate ease and duration of placing Laryngeal Mask Supreme (LM) and applying I-gel in geriatric patients without teeth. The secondary aim is to compare their effects on ventilation parameters.

  • 0 views
  • 14 Apr, 2022
  • 1 location
Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients (ANAPOD)

Our goal is to evaluate the efficacy of the Westmed system vs the Bair Hugger Blanket.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of Pectointercostal Facial Nerve Block for Postoperative Pain Management After Sternotomy in Pediatric Open Cardiac Surgery:A Randomized Controlled Trial

This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.

  • 0 views
  • 17 Oct, 2022
  • 1 location