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Found 8 clinical trials
A Phase 1 Study of ABC008 in Adult Patients With Inclusion Body Myositis (IBM)

An open-label, ascending dose study for adult patients with inclusion body myositis (IBM).

inclusion body myositis
  • 0 views
  • 05 Mar, 2022
  • 3 locations
Assessment of Safety and Acute Effects of a Lower-limb Powered Dermoskeleton in Patients With Neuromuscular Disorders (Exo-KGO1)

The aims of the current study are as follow: i) Evaluate the safety, usability, and acute efficiency of a programmable ambulation exoskeleton (KeeogoTM Dermoskeleton System, B-Temia Inc., Quebec, Canada) in patients with neuromuscular disorders, ii) Elaborate recommendations regarding usability criteria for safe and efficient use the device in patients with …

respiratory assessment
myopathy
Accepts healthy volunteers
  • 0 views
  • 24 Apr, 2022
  • 1 location
Assessment of Safety and Acute Effects of a Knee-hip Powered Soft Exoskeleton in Patients With Neuromuscular Disorders (Exo-NMD1)

The aims of the current study are as follow: i) Evaluate the safety, usability, and acute efficiency of a powered knee-hip dermoskeleton (MyoSuit, MyoSwiss, Zurich, Switzerland) in patients with neuromuscular disorders, ii) Elaborate recommendations regarding usability criteria for safe and efficient use the device in patients with neuromuscular disorders (e.g. …

myopathy
respiratory assessment
Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Study and Treatment of Inflammatory Muscle Diseases

This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms) associated with them. Inflammation and degeneration of skeletal muscles in these disorders leads to weakness and muscle wasting. The skin, lungs and other organs may also …

myopathy
rheumatic diseases
apheresis
biopsy incision
MRI
  • 839 views
  • 14 May, 2022
  • 1 location
Adult and Juvenile Myositis

This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their cause and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability. Children or adults with polymyositis or …

myopathy
pulmonary function test
MRI
weakness
corticosteroids
  • 152 views
  • 11 May, 2022
  • 4 locations
Investigating Genes in Patients With Polymyositis and Dermatomyositis

Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM)belong to a group of inflammatory muscle disorders, of unknown cause, that are characterised by skeletal muscle

myopathy
cytokines
weakness
arthritis
immunosuppressive agents
  • 105 views
  • 29 Sep, 2021
  • 1 location
Sporadic Inclusion Body Myositis Natural History Study

This is a prospective natural history study on patients with clinically defined sIBM. Participants will be assessed every 6 months over two years (five visits total). We will include 150 participants, enrolled across 13 sites, with sporadic IBM, diagnosed according to established criteria.

inclusion body myositis
  • 0 views
  • 03 Dec, 2021
  • 13 locations
Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders

, including patients with the following neuromuscular disorders: histologically confirmed inclusion body myositis (IBM), genetically confirmed late-onset Pompe disease (LOPD), genetically confirmed spinal

exercise tests
dyspnea
  • 0 views
  • 18 Jun, 2021
  • 1 location