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Found 431 clinical trials
COVID Protection After Transplant-Immunosuppression Reduction (CPAT-ISR)

> This group of patients is at high risk for severe COVID-19 disease due to pharmacologic immunosuppression and a high prevalence of non-transplant risk factors such as obesity and diabetes.

  • 0 views
  • 10 Jul, 2022
  • 14 locations
Comparison of Safety and Efficacy of Two Variants of Prolonged - Released Tacrolimus (Advagraf vs. Envarsus ) in Patients After Liver Transplantation : Single Center Randomised Control Trial

Adult patients after liver transplantation initially treated with traditional Tacrolimus variant- Prograf, switched on day 10 after orthotropic liver transplantation (OLTx) on prolonged released Tacrolimus variant in 1:1 ratio ( Advagraf vs. Envarsus)

tacrolimus
liver transplant
prograf
envarsus
  • 80 views
  • 05 Mar, 2022
  • 1 location
Extended Release Versus Immediate Release Tacrolimus Following Renal Allograft Failure to Reduce Allosensitisation

Study to compare once-daily extended release tacrolimus versus twice-daily immediate release tacrolimus following renal allograft failure to reduce the risk of allosensitisation

  • 0 views
  • 23 Jan, 2021
  • 1 location
RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients (OPTIMIZE)

Open label, randomized, multicenter, intervention trial comparing standard immunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen in combination with

tacrolimus
immunosuppressive agents
kidney transplant
calcineurin inhibitor
mycophenolate
  • 5 views
  • 16 May, 2022
  • 7 locations
RFA Plus Carrizumab vs Carrizumab Alone for HCC

The study aims to find whether patients with advanced HCC can get more benefits from RFA +PD-1 immunosuppressant (carrizumab) compared with carrizumab alone, considering with the result of PFS.

hepatocellular carcinoma
Accepts healthy volunteers
liver transplant
immunosuppressive agents
carcinoma
  • 0 views
  • 16 Feb, 2022
  • 1 location
Immunosuppression Management in Renal Transplant Recipients With Transplant Excellence Based on TruGraf Test

exclusion criteria will undergo immunosuppression reduction and will be followed closely to assess stability of graft function.

  • 0 views
  • 03 Sep, 2021
  • 1 location
Astaxanthin, Exercise Inflammation, Skin Health

Vigorous exercise can stress the body. Consuming special types of diet supplements may help the body recover better from exercise. This includes a bright red supplement called astaxanthin that is found in certain algae and causes the pink-red color in salmon. Astaxanthin is an antioxidant and may protect cells from …

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
Impact of Immunosuppression Adjustment on COVID-19 Vaccination Response in Kidney Transplant Recipients (ADIVKT)

vaccine response. The goal of this study is 1) examine whether transient immunosuppression reduction improves the immune response to a third dose of SARS-CoV-2 mRNA vaccine in kidney transplant recipients

  • 0 views
  • 24 Mar, 2022
  • 1 location
Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

effectiveness of adding eltrombopag to standard immunosuppressive therapy for severe aplastic anemia. Eligibility Individuals at least 2 years of age who

anemia
hematologic disorder
blood test
blood disorder
platelet count
  • 114 views
  • 21 Apr, 2022
  • 1 location
Trem-1 and Ultraviolet Radiation-induced Immune Suppression

The overall goal of this study is to determine novel mechanisms for ultraviolet light (UV)-induced suppression of the immune system in human subjects and to improve understanding of UV-induced skin carcinogenesis.

Accepts healthy volunteers
  • 0 views
  • 01 May, 2022