Found 331 clinical trials
Cyclophosphamide Added to Standard Immunosuppressive Therapy With Eltrombopag as Front-line Therapy in Patients With Severe Aplastic Anemia
This is a prospective, single-center, single-arm, phase 2 study. The aim of this study is to evaluate the efficacy and safety of Anti-lymphocyte globulin plus eltrombopag in combination with moderate-dose cyclophosphamide for severe aplastic anemia.
- 0 views
- 14 Aug, 2023
- 1 location
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia
. Patients with matched sibling donors for transplantation have a 80-90% chance of survival; however, a response rate with just immunosuppression for those patients lacking suitable HLA-matched related
- 20 views
- 18 Apr, 2022
- 2 locations
Different Immunosuppressive Treatment in iMN
The primary objective of this study is to compare the 24 month remission of different immunosuppressive therapies in the treatment of idiopathic membranous nephropathy (iMN)
- 2 views
- 30 Apr, 2022
- 1 location
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant
Immunosuppressive therapy is required to prevent organ rejection, however, dosing of immunosuppressive agents is complicated by patient-specific differences impacting the body's absorption and
- 0 views
- 19 Jun, 2022
- 2 locations
A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)
response without plasma exchange during the study. Participants who have an acute attack of iTTP will receive TAK-755 and immunosuppressive therapy during their stay at the hospital until they achieve a
- 0 views
- 12 Sep, 2023
- 1 location
Uterus Transplantation to Treat Infertility (OPRTUNTI)
to another woman. The woman who receives the transplant will take immunosuppression to keep the uterus and herself healthy. Because taking immunosuppressive medicine has side effects, uterus
- 4 views
- 29 Aug, 2023
- 1 location
Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients (IGNORANT)
inflammatory response and immunosuppression associating quantitative and functional alterations of innate and adaptive immune cells. These acquired immune dysfunctions have been associated with an increased
- 0 views
- 17 Sep, 2023
The Safety and Efficacy Study of Avatrombopag Switch in TPO-RA Refractory AA
cell transplantation (HSCT), were to another novel TPO-RA avatrombopta, 40-60 mg (weight <80 kg), in addition to maintaining the original immunosuppressive therapy ( CSA or equivalent immune potency
- 0 views
- 07 Oct, 2022
- 1 location
The Influence of Different Types of Physical Exercise on Immunosenescence in Elderly Persons
exercise-based/derived strategies to improve recovery of older patients suffering from immunosenescence and/or immune suppression. In this randomized controlled trial, the effects of resistance
- 0 views
- 25 Mar, 2022
- 1 location
Methotrexate in Patients With Early Rheumatoid Arthritis (MTXRA)
performed based on information given by a quality register. All patients with newly diagnosed RA are included in SRQ. Treatment options for RA include different types of immunosuppression and
- 20 views
- 27 Aug, 2023
- 6 locations