Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 436 clinical trials
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia

. Patients with matched sibling donors for transplantation have a 80-90% chance of survival; however, a response rate with just immunosuppression for those patients lacking suitable HLA-matched related

pancytopenia
cyclophosphamide
anemia severe
total body irradiation
graft versus host disease
  • 20 views
  • 18 Apr, 2022
  • 2 locations
Eltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA

adding eltrombopag to standard immunosuppressive therapy

  • 45 views
  • 26 Feb, 2022
  • 1 location
Combination Antiretroviral Therapy (cART) for PBC

will be performed in parallel using Emtricitabine (FTC)/Tenofovir Disoproxil (TDF) & Raltegravir in liver transplant recipients meeting all entry criteria except for use of immunosuppression.

  • 16 views
  • 25 Apr, 2022
  • 1 location
Pembrolizumab in Combination With Lenvatinib in Patients With Advanced Cholangiocarcinoma

development of cholangiocarcinoma (CCA) and chronic inflammation is a common underlying risk factor for CCA. Vascular endothelial growth factor (VEGF) signaling in CCA may lead to an immune suppression via

  • 0 views
  • 26 Aug, 2021
  • 2 locations
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

Immunosuppressive therapy is required to prevent organ rejection, however, dosing of immunosuppressive agents is complicated by patient-specific differences impacting the body's absorption and

  • 0 views
  • 19 Jun, 2022
  • 2 locations
RAFT - Clinical Trial of RAFT for Aniridia Related Keratopathy

, investigations such as digital photography of the eye and examinations of the surface of the eye. Participants will be required to stay on the immune suppression therapy for the duration of the trial

  • 0 views
  • 20 Dec, 2021
  • 1 location
Impact of Preoperative Single Corticosteroid Flash on Morbidity After Colorectal Resection: Monocentric Prospective Pilot Study (CORTICOLON)

term survival for cancer patients. Perioperative inflammation leads to hypercatabolism, denutrition and immunosuppression, all of which are associated to postoperative infection. Data from various

  • 0 views
  • 26 Feb, 2022
  • 1 location
The Influence of Different Types of Physical Exercise on Immunosenescence in Elderly Persons

exercise-based/derived strategies to improve recovery of older patients suffering from immunosenescence and/or immune suppression. In this randomized controlled trial, the effects of resistance

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Prospective Multicentric Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate Cyclophosphamide) in Large Granular Lymphocytes Leukemia

consensual treatment options. If first and second line treatments are based on the use of immunosuppression with methotrexate, cyclophosphamide, or cyclosporin A, no molecule has proven superiority over

  • 35 views
  • 05 Sep, 2021
  • 65 locations
Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis (TOLERANT)

Rationale: In rheumatoid arthritis, immune cells cause joint inflammation and destruction in response to autoantigens. Immunosuppressive therapies offer relief but fail to induce tolerance to

remission
DMARD
prednisone
glucocorticoids
antirheumatics
  • 0 views
  • 10 Mar, 2022
  • 1 location