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Found 227 clinical trials
Tarceva Italian Lung Optimization tRial

The aim of this study is to assess the superiority of docetaxel in comparison to erlotinib in second line in wild-type EGFR tumour patients.

docetaxel
EGFR
tarceva
erlotinib
  • 39 views
  • 07 Nov, 2020
  • 47 locations
Accuracy of VABB Elite 10G Versus BARD 14G CNB

In this study, patients whose breast ultrasound showed a space-occupying lesion and needed biopsy to clarify the pathology were selected as the research subjects. This study aims to determine whether Vacuum-assisted biopsy device Elite is superior to the traditional BARD ejection type air core needle in the diagnosis of breast …

  • 0 views
  • 04 Nov, 2020
  • 1 location
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer

breast cancer. The hypothesis is that FFNP SUVmax from PET/MRI will correlate well against the semi-quantitative PR immunohistochemistry score.

progesterone receptor
progesterone
immunohistochemistry
  • 0 views
  • 20 Dec, 2020
  • 1 location
Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer

will be admitted to 6 weeks treatment with RAD001 10 mg/day followed by either radical prostatectomy or radiotherapy combined with hormonal treatment. Immunohistochemistry with antibodies

PTEN
adenocarcinoma
castration-resistant prostate cancer
adenocarcinoma of prostate
prostatectomy
  • 3 views
  • 07 Nov, 2020
  • 1 location
The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic Asthma

epithelial cells as the primary outcome. Secondary outcomes such as: Inflammatory cytokines, immunologic phenotype and immunohistochemistry will be investigated in bronchial biopsies, blood, bronchoalveolar

  • 1 views
  • 24 Jan, 2021
  • 1 location
Atezolizumab and BCG in High Risk BCG na ve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE)

-specific CD8 T-cells, impairing cytokine production and diminishing the toxicity of activated T-cells. PD-L1 expression by immunohistochemistry using the Ventana SP142 assay on tumor-infiltrating immune

tumor cells
expression by immunohistochemistry
transurethral resection
carcinoma in situ
carcinoma
  • 0 views
  • 04 Nov, 2020
Cladribine With Simultaneous or Delayed Rituximab to Treat Hairy Cell Leukemia

antibody dependent cytotoxicity (ADCC or CDC). Patients in complete remission (CR) to cladribine have minimal residual disease (MRD) by immunohistochemistry of the bone marrow biopsy (BMBx IHC), a

  • 38 views
  • 17 Jan, 2021
  • 1 location
Immune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer (TNBC) Patients

This is a single center non-blinded randomized multi-cohort non-comparative phase II trial with a Simon's two-stage design.

anthracyclines
brain metastases
metastasis
breast cancer
triple negative breast cancer
  • 0 views
  • 28 Sep, 2020
  • 1 location
Lenalidomide Combined With R-CHOP(R2-CHOP) in Newly Diagnosed Double-expressor Diffuse Large B-Cell Lymphoma Patients

In this phase II study, the investigators are aiming to explore lenalidomide combined with R-CHOP (R2-CHOP) in newly diagnosed double-expressor Diffuse Large B-Cell Lymphoma patients (DLBCL)

  • 1 views
  • 23 Jan, 2021
  • 1 location
A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

The study is investigating efficacy, safety and tolerability of DNA-damage Response Agents (or Combinations), in participants with advanced/metastatic solid malignancies whose tumours contain molecular alterations.

  • 0 views
  • 19 Dec, 2020
  • 16 locations