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Found 13 clinical trials
Intravenous Gammaglobulin for Sickle Cell Pain Crises

The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease.

  • 41 views
  • 07 Nov, 2020
  • 1 location
Methylprednisolone Pulse Therapy for Coronary Artery Dilatation or Aneurysm Formation in Kawasaki Disease

In this study, the investigator plan to prescribe Methylprednisolone pulse therapy in Kawasaki disease patients with coronary artery lesions or aneurysm formation beyond acute stage to investigate the role for vasculitis of KD or regression of dilatation.

vasculitis
methylprednisolone pulse therapy
coronary artery aneurysm
aneurysm
igiv
  • 33 views
  • 25 Jan, 2021
  • 1 location
Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

This randomized phase III trial studies rituximab after stem cell transplant and to see how well it works compared with rituximab alone in treating patients with in minimal residual disease-negative mantle cell lymphoma in first complete remission. Monoclonal antibodies, such as rituximab, may interfere with the ability of cancer cells …

bendamustine
cyclophosphamide
prednisone
chop regimen
mantle cell lymphoma
  • 367 views
  • 31 Jan, 2022
  • 238 locations
Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency

The purpose of this study is to evaluate the pharmacokinetics and safety of Immune Globulin Intravenous (Human) GC5107 in pediatric subjects with Primary Humoral Immunodeficiency (PHID

  • 0 views
  • 22 Jun, 2021
  • 5 locations
Intravenous Gammaglobulin for Sickle Cell Pain Crises

The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease. Funding Source: Food and

acute pain
thalassemia
narcotics
  • 21 views
  • 26 Jan, 2022
  • 1 location
Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies

cumulative incidence of acute and chronic GvHD. Thirty patients will receive cyclophosphamide while twenty patients will receive antihuman T-lymphocyte immune globulin (ATG).

  • 0 views
  • 22 Jan, 2021
  • 1 location
Stop Hep B @ Birth

hepatitis B virus: antenatal tenofovir, and timely newborn administration of hepatitis B birth dose vaccine and hepatitis B immune globulin; Component II aims to achieve high coverage of screening

encephalopathy
hepatitis
cirrhosis
hepatitis b immune globulin
tenofovir
  • 0 views
  • 15 Aug, 2021
  • 1 location
Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

Immunoprophylaxis with two hepatitis B vaccinations following the hepatitis B immune globulin (HBIg) and hepatitis B vaccine at birth is largely effective in protecting infants from hepatitis B

tenofovir disoproxil fumarate
hepatitis
hepatitis b immune globulin
hbeag
tenofovir
  • 81 views
  • 02 Mar, 2022
  • 7 locations
Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

This phase II trial tests whether treosulfan, fludarabine, and rabbit antithymocyte globulin (rATG) work when given before a blood or bone marrow transplant (conditioning regimen) to cause fewer complications for patients with bone marrow failure diseases. Chemotherapy drugs, such as treosulfan, work in different ways to stop the growth of …

fludarabine
shwachman-diamond syndrome
tacrolimus
methotrexate
platelet count
  • 0 views
  • 11 May, 2022
  • 10 locations
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

This phase I trial investigates the side effects and effectiveness of chemotherapy followed by a donor (allogeneic) stem cell transplant when given to patients with high grade brain cancer. Chemotherapy drugs, such as fludarabine, thiotepa, etoposide, melphalan, and rabbit anti-thymocyte globulin, work in different ways to stop the growth of …

  • 0 views
  • 02 Mar, 2021
  • 1 location