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Found 82 clinical trials
The Hong Kong CML Registry

Chronic myeloid leukaemia (CML) is a malignant disorder of the haematopoietic system. It is characterized by the chromosomal translocation between chromosomes 9 and 22, resulting in the formation of the Philadelphia chromosome which contains the BCRABL1 fusion gene. The projected prevalence of CML is rising steadily, due to the significantly …

philadelphia chromosome
tyrosine
leukemia
  • 24 views
  • 12 Feb, 2022
  • 1 location
Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies.

The aim of this project is to test whether low levels of BcrAbl1, despite the presence of resistance mutations, are related to high levels of innate CD8+ T cells, in the hypothesis that these cells have an anti-tumor role. This research aims to investigate: An association between the rate of …

myeloid leukemia
philadelphia chromosome
leukemia
kinase inhibitor
flow cytometry
  • 0 views
  • 30 Jul, 2021
  • 1 location