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Found 79 clinical trials
Imatinib in Acute Ischaemic Stroke

A clinical trial comparing treatment with Imatinib to placebo when administered within 8 hours of stroke onset for 6 days, in addition to conventional stroke treatment after acute ischaemic

  • 16 views
  • 25 Jan, 2021
  • 26 locations
Imatinib Versus Imatinib and Peg-Interferon in Patients With Ph+ CML and Complete Cytogenetic Response After Imatinib Therapy

The study is controlled and randomized in Philadelphia-positive chronic myeloid leukemia (Ph+ CML) patients with complete cytogenetic response after more than one year of imatinib therapy

interferon
remission
leukemia
imatinib
  • 8 views
  • 07 Nov, 2020
  • 1 location
Positioning Imatinib for Pulmonary Arterial Hypertension

to pump blood through the lungs. While current treatments relieve some of the symptoms, they do not stop or reverse the disease in the affected blood vessels. Imatinib is a medicine licensed for some

  • 0 views
  • 15 Mar, 2021
  • 8 locations
Comparing Imatinib Standard Dose With Imatinib High Dose Induction in Pretreated Chronic Myeloid Leukemia (CML) Patients in Chronic Phase

imatinib (Glivec®) in pretreated Philadelphia chromosome- positive (Ph+)/BCR-ABL+ CML patients in chronic phase.

gleevec
leukemia
philadelphia chromosome
interferon
imatinib
  • 11 views
  • 07 Nov, 2020
  • 1 location
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement

The purpose of this study is to verify effect and tolerability of imatinib on pulmonary and skin fibrosis in patients affected by systemic sclerosis.

pulmonary involvement
fibrosis
cyclophosphamide
progressive systemic sclerosis
pulmonary function test
  • 33 views
  • 07 Nov, 2020
  • 1 location
Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

serum bilirubin level
secondary acute myeloid leukemia
mitoxantrone
refractory acute myeloid leukemia (aml)
  • 15 views
  • 07 Nov, 2020
  • 1 location
Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE

less than 20%). The effectiveness of imatinib for hematologic responses in patients with Ph + (observed in phase I and II) led to its use in phase III trials in combination with chemotherapy. They saw

  • 103 views
  • 03 Feb, 2021
  • 112 locations
Treatment Modification Based on Early Assessment of CML Patients

The investigators will check the feasibility of using early molecular response for making treatment decisions. Patients diagnosed with chronic myeloid leukemia will commence imatinib treatment

leukemia
philadelphia chromosome
nilotinib
kinase inhibitor
philadelphia chromosome positive chronic myelogenous leukemia
  • 5 views
  • 08 Nov, 2020
  • 1 location
Treatment of Acute Lymphoblastic Leukemia Ph '(BCR / ABL) Positive Patients Aged > 55 Years

associated with imatinib or dasatinib has acceptable tolerability in elderly patients. To determine whether this association can increase the rate and quality of referrals to the results of the

  • 1 views
  • 28 Jan, 2021
  • 1 location
  • 0 views
  • 26 Jan, 2021
  • 7 locations