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Found 14 clinical trials
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.

ileocolitis
tumour necrosis
tumor necrosis factor
tumor necrosis factor alpha
ileitis
  • 14 views
  • 22 Mar, 2021
  • 9 locations
Mesenteric SParIng Versus Central mesenterectomY in Ileocolic Resection for Terminal Ileitis in Crohn's Disease

The aim of this multicenter randomised controlled trial is to analyse the six month endoscopic recurrence following a mesenteric sparing versus a central mesenterectomy performing an ileocolic resection for CD.

antibiotics
ct enterography
corticosteroids
ileitis
anti-tnf therapy
  • 0 views
  • 25 Jan, 2021
  • 1 location
the Prophylaxis of Recurrent Pouchitis After Fecal Microbiota Transplant in UC With Ileo-anal Anastomosis

Ulcerative colitis (UC) is a chronic inflammatory digestive (IBD) disease medically treated with corticosteroids, aminosalicylates, immunomodulators, and biologics. Almost one third of UC patients will require surgical interventions because of fulminant colitis, dysplasia, cancer, or medical refractory diseases. Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the current standard surgical …

  • 0 views
  • 23 Jan, 2021
  • 10 locations
Prospective Dietary Therapy Using Crohn's Disease Exclusion Diet for Ileal Pouch Anal Anastomosis Patients

Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with ulcerative colitis (UC) who require surgery. Inflammation of the ileal pouch (pouchitis) occurs in up to 60% of pouch patients. Although, pouchitis patients are former UC patients, the disease occurs in the small intestine, …

  • 0 views
  • 04 Jun, 2021
  • 1 location
Stelara fOr ChRonic AntibioTic rEfractory pouchitiS

To evaluate the efficacy and safety of ustekinumab in the treatment of chronic antibiotic refractory and relapsing pouchitis.

  • 0 views
  • 06 May, 2021
  • 2 locations
Fecal Microbiota Transplantation for Pouchitis

This is a randomized double-blind placebo controlled trial involving a single centre (McMaster University) recruiting patients from Hamilton, ON and the surrounding regions, to evaluate whether fecal microbiota transplantation once weekly for six weeks increases the remission rate compared to placebo in patients with active pouchitis.

  • 35 views
  • 26 Jan, 2021
  • 1 location
Treating Chronic Pouchitis With a Low FODMAP Diet

We aim to determine whether low FODMAP diet in patients with chronic pouchitis will improve symptoms and pouch inflammation.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study of the Safety and Efficacy of AMT-101 in Subjects With Pouchitis

Phase 2 Study Investigating the Efficacy of AMT-101 in Subjects with Chronic Antibiotic-resistant Pouchitis

  • 0 views
  • 14 Aug, 2021
  • 31 locations
Tofacitinib For Treatment Of Chronic Pouchitis

A phase 2 pilot study to evaluate the effectiveness of tofacitinib in subjects with chronic pouchitis

  • 0 views
  • 10 May, 2021
  • 1 location
GM-CSF Fosfomycin and Metronidazole for Pouchitis in Ulcerative Colitis Patients After Restorative IPAA Surgery

This study will examine whether the application of GM-CSF, fosfomycin and metronidazole locally in the pouch is safe and effective in the treatment of pouchitis for patients with ulcerative colitis, and whether treatment changes the microbiome of the pouch.

  • 0 views
  • 20 Sep, 2021
  • 1 location