Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 310 clinical trials
TocIlizumab in Chronic Antibody-mediated Rejection in Kidney Transplant Recipients (INTERCEPT)

This multi-center study is an investigator-driven randomized controlled parallel group open-label clinical trial designed to evaluate the efficacy of addition of anti-IL-6 antibody tocilizumab

  • 0 views
  • 22 Mar, 2022
Allografts in Surgery of the Main Arteries

weeks, 3 weeks, 4 weeks, 5 weeks, 6 weeks). Markers of endothelial dysfunction (IL-6, endothelin-1, 6-keto-prostaglandin F1alfa, eNOS) will be evaluated in patients with critical ischemia who undergo

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 2 Randomized Double-Blinded Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in Subjects With Indolent Systemic Mastocytosis

Background Mast cells help the body fight disease and heal wounds. People with indolent systemic mastocytosis (ISM) make too many mast cells. This causes pain, tiredness, digestive problems, and other symptoms. Researchers think the drug sarilumab could help. Objective To see if sarilumab is a safe and effective treatment for …

  • 62 views
  • 13 Oct, 2022
  • 1 location
Effect of Preoperative Carbohydrate Loading on Post-operative Insulin Resistance After Donor Hepatectomy.

It's a randomized control trial to compare the effect of preoperative carbohydrate loading versus fasting on post operative insulin resistance after donor hepatectomy in terms of donor outcomes. Investigator will analyze the data and elucidate the value of post operative insulin resistance in reducing the occurrence of complications, length of …

Accepts healthy volunteers
  • 0 views
  • 07 Apr, 2022
  • 1 location
Inhibition of Bradykinin in COVID-19 Infection With Icatibant (ICASARS)

There is excess accumulation of bradykinin during symptomatic SARS CoV-2 lung infection. Bradykinin causes oedema in the lung, with reduced oxygen. It also causes vasodilation, hypotension and cytokine release.

  • 0 views
  • 19 Jun, 2022
  • 1 location
Health Benefits of Whole-body Vibration (VIBE-Rx)

The overall goals of this pilot investigation are to determine 1) the feasibility of conducting home based WBV studies, and 2) to determine if sub-acute home based WBV can improve a) exercise capacity, b) conduit- and micro- vascular function, and c) skeletal muscle function.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Clinical Pharmacology and Target Validation of A Bioactive Dietary Polyphenol Preparation (BDPP) For Stress-Related Disorders

This study will characterize the clinical pharmacology of a select bioactive polyphenol-rich preparation (Bioactive Dietary Polyphenol Preparation, BDPP) comprised of a select Concord grape juice (CGJ), a select grape seed polyphenol extract (GSPE) and trans-resveratrol (RSV).

Accepts healthy volunteers
  • 0 views
  • 28 Oct, 2022
  • 1 location
Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

To assess the efficacy of mindfulness-based intervention (MBI) intervention in the treatment of moderate or severe fatigue in patients with primary biliary cholangitis (PBC).

ursodiol
fatigue
cholangitis
cirrhosis
  • 1 views
  • 07 Oct, 2022
  • 1 location
The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome

According to current IBS management guidelines, probiotic administration reduces IBS-associated symptoms and improves the quality of life. The purpose of this study is to assess the effects of the combined formulation comprising microencapsulated sodium butyrate and a probiotic mixture of two Lactobacillus strains (L. rhamnosus and L. acidophilus) and three …

nortriptyline
abdominal pain
acidophilus
longum
maltodextrin
  • 0 views
  • 29 Aug, 2021
  • 1 location
Sacral Nerve Stimulation for Mild-to-Moderate or Refractory Rheumatoid Arthritis

This pilot study will assess the efficacy of sacral never stimulation (SNS) for the treatment of adult patients with active, mild-to-moderate rheumatoid arthritis or those with refractory disease. The study will enroll 60 subjects in a single center. All eligible subjects will be randomly divided into two groups at a …

Accepts healthy volunteers
antirheumatics
  • 0 views
  • 13 Mar, 2022
  • 1 location