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Found 11 clinical trials
DianaWeb: Before and After Study Online Based Participatory Research on Breast Cancer Women

DianaWeb is a community-based participatory research (CBPR) offered to Italian breast cancer patients. The aim of the study is the evaluation of effectiveness of a lifestyle and nutrition intervention to improve the prognosis. DianaWeb study utilizes an interactive website - - to monitor patient life-style, and to obtain clinical, …

  • 07 Oct, 2021
  • 1 location
Chinese Medicine WT for Spinocerebellar Ataxia Type 3

Spinocerebellar ataxia type 3 (SCA3) is one of autosomal dominant hereditary ataxias. Standing imbalance, unsteady gait, dysmetria, fatigue, and depression would occur gradually. There are no effective treatment or palliative methods for patients in the present days. However, low-dose growth hormone, or its downstream product, insulin-like growth factor I (IGF-1), …

  • 01 Nov, 2021
  • 1 location
Gene Expression Changes In Young and Geriatric Skin

This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults. Sunlight exerts many effects on the body. There is evidence that in response to ultraviolet …

Accepts healthy volunteers
  • 07 Apr, 2022
  • 1 location
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents

The primary aim of this proposal is to determine the effects of soluble corn fiber (SCF) supplementation for 1 year on bone metabolism in growing adolescents compared to controls. For the proposed study, a randomized double-blinded placebo controlled clinical trial will be conducted in 236 healthy adolescents aged 10-13 years, …

body mass index
Accepts healthy volunteers
bone mineral density
  • 27 Feb, 2022
  • 1 location
An Exploratory Study of Increased Preterm Arginine INTake (PAINT18) (PAINT18)

PAINT18 is a nutrition study focusing on the effect of arginine supplementation on immune function in preterm infants. The investigators will explore the effect of current intravenous feeding (parenteral nutrition (PN) formulations on blood arginine levels and the genes that are involved in body nutrition and fighting infection in premature …

  • 13 Apr, 2022
  • 1 location
Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly.

Background: Immunosenescence is an aging-dependent phenomenon underlying age dependent deterioration in the function of the immune system, characterized by a decline in B and T cells with a relative increase in natural killer (NK) cells. Aging also promotes chronic inflammation accompanied by increased levels of pro-inflammatory cytokines. Both immunosenescence and …

Accepts healthy volunteers
  • 31 Oct, 2021
  • 1 location
Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis

Background: Adipose tissue fibrosis denotes excessive pathological accumulation of extracellular matrix (ECM) in adipose tissue and is a marker of dysfunction. Growth hormone (GH) activates adipose tissue lipolysis and stimulates collagen synthesis in lean tissues. Intriguingly, we have novel pilot data to suggest that GH excess (acromegaly) also induces reversible …

  • 10 Sep, 2021
  • 1 location
INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer

Exercise has been established to be safe and result in improved physical function and quality of life for most individuals with cancer. However, little information exists regarding whether exercise can increase overall survival and reduce disease progression, events related to cancer spreading to the bones (e.g. bone fracture, spinal cord …

bone metastases
luteinizing hormone-releasing hormone agonist
  • 25 Jan, 2021
  • 4 locations
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

levels of growth hormone, IGF-I (a hormone made in response to growth hormone), and a pituitary adenoma visualized on an MRI. Patients would have already agreed to have their

somatomedin c
tolerance test
oral glucose tolerance test
growth hormone
insulin-like growth factor
  • 24 Jan, 2022
  • 1 location
ACRODAT Prospective Evaluation Study

parameters (IGF-I level, tumour status, comorbidities, symptoms and Quality of life) to evaluate the patient's health status. The purpose of this post marketing surveillance study is to prospectively

insulin-like growth factor
somatomedin c
  • 24 May, 2022
  • 1 location