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Found 115 clinical trials
Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286

expression in idiopathic pulmonary fibrosis (IPF), cirrhosis, and cardiac fibrosis.

biopsy of liver
fibrosis
idiopathic pulmonary fibrosis
hepatic fibrosis
pulmonary fibrosis
  • 0 views
  • 25 Mar, 2022
  • 1 location
Xenon MRI and Progressive ILD

The XENON ILD study is a single arm, un-blinded study at Duke University enrolling patients with non-idiopathic pulmonary fibrosis (IPF) progressive fibrosis (PF) interstitial lung disease (ILD

progressive systemic sclerosis
ciclosporin
azathioprine
immunosuppressant
pneumonia
  • 0 views
  • 04 Oct, 2022
  • 1 location
Palliative Care Planner (PCplanner)

addressing needs and promoting advance care planning discussions among patients with idiopathic pulmonary fibrosis and their clinicians.

idiopathic pulmonary fibrosis
fibrosis
pulmonary fibrosis
interstitial lung disease
  • 0 views
  • 22 Apr, 2022
  • 1 location
A Phase 1, Evaluate the Safety, Tolerability, and Pharmacokinetics of INS018_055 in Healthy Subjects

The sponsor is planning to conduct a Phase 1, randomized, double-blind, placebo-controlled, oral single and multiple ascending-doses, parallel group study to evaluate the safety, tolerability and PK of INS018_055 in healthy subjects. The study will be conducted in 1 clinical site in the New Zealand, consisting of 2 parts: Part …

body mass index
vasectomy
tubal ligation
follicle stimulating hormone
Accepts healthy volunteers
  • 0 views
  • 14 Apr, 2022
Comparison of the 1-min Sit-to-Stand Test to the 6-minute Walk Test in the Respiratory Functional Assessment of Pulmonary Fibrosis: a Cross-over Trial (LaMinute_FIP)

pulmonary fibrosis (IPF) is the most common and most severe pulmonary fibrosis. Other pulmonary fibroses are mainly represented by non-specific interstitial lung disease, pulmonary fibroses associated with

walk tests
pulmonary disease
sarcoidosis
dyspnea
idiopathic pulmonary fibrosis
  • 0 views
  • 21 Oct, 2022
  • 1 location
A Double-blind, Randomized, Placebo-controlled Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of Oral AZD5055 Following Single and Multiple Ascending Doses

This is a phase I, First-in-Human study in healthy participants, performed at a single study center, consisting of 2 parts: Part 1 is a single ascending dose (SAD) study and Part 2 is a multiple ascending dose (MAD) study.

Accepts healthy volunteers
  • 4 views
  • 10 Oct, 2022
  • 1 location
Pirfenidone to Prevent Fibrosis in ARDS. A Randomized Controlled Trial - PIONEER (PIONEER)

disease affects ARDS patients even years after acute phase resolution. Pirfenidone is an oral anti-fibrotic drug, approved and largely used for treatment of idiopathic pulmonary fibrosis (IPF). The

acute respiratory distress
fibrosis
acute lung injury
pulmonary fibrosis
  • 0 views
  • 24 Oct, 2022
  • 2 locations
Pirfenidone for the Reduction of Metabolic, Inflammatory and Fibrogenic Activity in Complicated Silicosis

have been developed and have demonstrated their ability to decrease pulmonary fibrogenic activity in diseases such as Idiopathic Pulmonary Fibrosis (IPF). This has been a milestone in the treatment of

  • 0 views
  • 25 Mar, 2022
A Multi-Cohort, Randomised, Placebo-Controlled Phase 2a Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Ascending Doses of RXC007 in Patients With Idiopathic Pulmonary Fibrosis

The purpose of the study is to assess the safety and tolerability of RXC007 when given for 12 weeks (84 days), alone and in combination with nintedanib or pirfenidone.

  • 0 views
  • 27 Oct, 2022
  • 1 location
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

The purpose of this study is to determine whether a lung transplantation prior to bone marrow transplantation (BMT) would allow for restoration of pulmonary function prior to BMT, allowing to proceed to BMT, to restore hematologic function.

a hemoglobin
lung transplant
COPD
emphysema
pulmonary disease
  • 115 views
  • 26 Mar, 2022
  • 2 locations