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Found 101 clinical trials
Molecular Diagnosis of Idiopathic Interstitial Pneumonias: a Prospective Study

of idiopathic pulmonary fibrosis (IPF) vs. non-specific interstitial pneumonia (NSIP), the 2 main types of idiopathic interstitial pneumonias (IIPs). The investigators hypothesize that pre

ct scan
interstitial lung disease
lung biopsy
  • 07 Feb, 2022
  • 1 location
Effects of Pulmonary Diseases and Their Treatment on Cardiac Function

While the bidirectional relationship between the lung and the right heart are well studied, the cardiopulmonary interactions between the lung and the left heart are largely unresearched and not well understood. However, in recent years, there is a growing evidence that partially explains the bidirectional interaction between COPD and left …

pulmonary disease
  • 05 Jul, 2022
  • 1 location
ILD-SARDs Registry and Biorepository

A complex interaction between demographic, environmental and genetic mechanisms impact the onset, severity and outcome of ILD-SARDs through dysregulation of the immune system and lung pro-biotic pathways. Comorbidity and genetic risk indicate that there are overlapping pathogenic mechanisms among SARDs, some of which underlie ILD in different SARDs. The purpose …

lung disease
chest ct
connective tissue disease
bronchoalveolar lavage
  • 18 Sep, 2021
  • 1 location
The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia

This is a prospective observational study designed to evaluate Immature Platelet Fraction or Immature Platelet Count and Platelet Function Analyzer-100/200 Closure Time-ADP (in vitro bleeding time) as markers of bleeding risk in thrombocytopenic preterm neonates admitted to the Neonatal Intensive Care Unit.

  • 24 Sep, 2021
  • 8 locations
Inflammatory Profiling in Chronic Lung Disease

The aim of this study is to investigate the underlying inflammatory profile in patients with chronic lung disease and determine the association pulmonary hypertension.

  • 27 Jan, 2021
  • 1 location
The Clinical Course of Interstitial Pneumonia With Autoimmune Features

Interstitial pneumonia with autoimmune features (IPAF) is a chronic interstitial lung disease (ILD) with some laboratoristic and/or clinical features of autoimmune disease, but without meeting criteria of connective tissue disease (CTD), and with no other causes of ILD. Despite recent efforts to standardize the diagnosis of IPAF, subjects with IPAF …

lung transplant
  • 20 Apr, 2022
  • 1 location
Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research

A major goal of this protocol is to support biomarker studies in advanced lung diseases, lung transplantation care, and to improve our understanding of the effects of viral and other infectious exposures to outcomes in our lung transplant and ALD patient populations.

lung transplant
  • 03 Aug, 2021
  • 1 location
Sjogren's Lung Study

Lung involvement in Sjgren's syndrome is common and causes reduced quality of life and increased mortality. Sjgren's syndrome-related lung diseases (SS-RLD) are classified and treated as the primary lung diseases they resemble. Whether this approach is optimal has not been evaluated thoroughly. A critical gap in knowledge is knowing whether …

  • 21 Apr, 2021
  • 1 location
Association of Platelet Parameters With Bleeding Severity in Children With ITP (ITP-APPS)

Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan. In a single-center study, platelet parameters including the immature platelet fraction, the absolute immature platelet count , and …

autoimmune thrombocytopenia
platelet count
  • 19 Jun, 2022
  • 3 locations
Interstitial Lung Disease Registry Construction

The purpose of this study is investigating the clinical course, treatment course, and prognosis of patients with interstitial lung disease.

pulmonary fibrosis
pulmonary disease
interstitial lung disease
  • 21 Jan, 2021