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Found 101 clinical trials
Featured trial
Study to evaluate HZN-825 in patients with Idiopathic Pulmonary Fibrosis (IPF)

The goal is to determine the efficacy, safety and tolerability for 360 patients with Idiopathic Pulmonary Fibrosis (IPF) assigned to either one of 2 dose regimens of HZN-825 (administered once

pneumonia
diffusion capacity of the lung for carbon monoxide
emphysema
  • 10 views
  • 18 Oct, 2022
  • 53 locations
Featured trial
Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

  • 2267 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that becomes worse over time. There is currently no effective treatment for it. Researchers

chest x-ray
walk tests
idiopathic pulmonary fibrosis
x-rays
chest ct
  • 178 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India

of Rotarix/placebo PO at monthly intervals starting at 6 to <8 weeks of age, administered concomitantly with EPI/UIP vaccines. To maintain the blind, infants allocated to the TV P2-VP8 vaccine arm

Accepts healthy volunteers
  • 0 views
  • 15 Feb, 2022
  • 1 location
Efficacy of Steroid Pulse Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Admitted in ER

Idiopathic pulmonary fibrosis is the most severe form of interstitial lung disease. It is known that the prognosis is poor due to extensive inflammation and fibrosis of the lung parenchyma. In

  • 2 views
  • 18 Aug, 2021
Lysophosphatidic Acid / Autotaxin Axis in Rheumatoid Lung Disease

once symptomatic. Unfortunately, there is no medical care recommendation so far as the pathophysiology is unknown. However, ILD share many similarities with idiopathic pulmonary fibrosis (IPF).

interstitial lung disease
  • 4 views
  • 05 Aug, 2021
  • 1 location
PFOX: Pulmonary Fibrosis Ambulatory Oxygen Trial (PFOX)

The fibrotic interstitial lung diseases (fILD) are characterised by lung scarring, distressing breathlessness and poor health-related quality of life. Exertional desaturation (low blood oxygen during exercise) is a hallmark of fILD, occurring in over 50% of patients. It is sometimes treated with ambulatory oxygen therapy (AOT), which involves breathing supplemental …

  • 3 views
  • 12 Feb, 2022
  • 1 location
Hyperpolarized Xenon-129 MR Imaging of the Lung

Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial and vascular dysfunction, and to cause murine phenotypes similar to those of human COPD. Recently, "spiked" vape juice has been linked …

  • 27 views
  • 26 Jan, 2021
  • 1 location
Sputum Microbiota and the Association With Clinical Parameters in Steady-state Acute Exacerbation and Convalescence of Bronchiectasis

Study 1 is a cross-sectional investigation. Patients with clinically stable bronchiectasis (symptoms, including cough frequency, sputum volume and purulence, within normal daily variations) will undergo baseline assessment consisting of history taking, routine sputum culture, 16srRNA pyrosequencing, measurement of sputum inflammatory markers, oxidative stress biomarkers and MMPs, and spirometry. Microbiota taxa …

sputum culture
cough
antibiotics
grip
antibiotic therapy
  • 29 views
  • 23 Jan, 2021
  • 1 location