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Found 86 clinical trials
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

children with acute MSK limb injuries. The pain medicines the investigators are studying are ibuprofen (Advil/Motrin), acetaminophen (Tylenol/Tempra), and hydromorphone (Dilaudid). This study will

  • 8 views
  • 10 May, 2021
  • 12 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on …

  • 8 views
  • 10 Aug, 2021
  • 4 locations
Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion

RATIONALE: Morphine and ibuprofen help lessen pain caused by pleurodesis. It is not yet known whether one drug is more effective than the other in lessening pleurodesis-related pain or

pleurodesis
  • 27 views
  • 07 Nov, 2020
  • 1 location
Oral Versus Rectal Ibuprofen for Fever in Young Children - a Randomized Control Study.

fever to be the most terrifying symptom. Ibuprofen is an effective and safe treatment for febrile children. Until recently ibuprofen was available only in tablets suspension and as a liquid

ibuprofen
  • 4 views
  • 07 Nov, 2020
  • 1 location
Paracetamol Versus Ibuprofen in Premature Infants With Hemodynamically Significant Patent Ductus Arteriosus

Multicentric, double-blind clinical trial, which will evaluate the efficacy of iv paracetamol versus standard treatment with ibuprofen in the closure of patent ductus arteriosus in the preterm

  • 0 views
  • 23 Jan, 2021
  • 6 locations
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block

  • 27 views
  • 23 Jan, 2021
  • 1 location
Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma

there is little data about the best treatment for children. The ibuprofen and ketorolac are respectively the most used and one of the most powerful NSAIDs. In literature, there is no direct comparison

  • 0 views
  • 23 Jan, 2021
  • 3 locations
Adding a Second Drug for Febrile Children Treated With Acetaminophen

fever to be the most terrifying symptom. Acetaminophen and ibuprofen are both effective and safe treatments for febrile children. In order to achieve better temperature control and to avoid

ibuprofen
  • 5 views
  • 07 Nov, 2020
  • 1 location
NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures

The purpose of this study is to determine if using the combination of acetaminophen (also known as Tylenol) and ibuprofen (also known as Motrin or Advil) will provide equal or better pain

  • 0 views
  • 17 Sep, 2021
  • 1 location
Supracondylar Post-Operative Pain Study

surgery. Patients will be randomized to receiving acetaminophen and ibuprofen or acetaminophen and oxycodone. Parents will not be blinded to the acetaminophen but both investigators, parents and the

  • 0 views
  • 10 May, 2021
  • 1 location