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Found 263 clinical trials
Randomised Evaluation of COVID-19 Therapy (RECOVERY)

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only), Convalescent plasma, Casirivimab+Imdevimab, Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin, Sotrovimab, Molnupiravir, Paxlovid or Anakinra (children only) prevents death in patients with COVID-19.

hydroxychloroquine
pneumonia
azithromycin
cough
corticosteroids
  • 0 views
  • 19 Apr, 2022
  • 6 locations
30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants (HiLo)

Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8 percent of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks' gestation. At this gestational age, the lungs are not fully developed and it is not …

  • 2 views
  • 29 Jul, 2023
  • 7 locations
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation (STEPCARE)

The STEPCARE-trial is a 2x2x2 randomised trial studying patients who have been resuscitated from cardiac arrest and who are comatose. It will include three different interventions focusing on sedation targets, temperature targets and mean arterial pressure targets.

  • 0 views
  • 10 Sep, 2023
  • 1 location
Prostate Hypoxia FAZA

The purpose of this study is to look for low levels of oxygen (hypoxia) in prostate cancer using a special x-ray test called a positron emission tomography (PET)scan. Hypoxia may have an effect

prostate specific antigen
hormone therapy
prostate cancer metastatic
adenocarcinoma
adenocarcinoma of prostate
  • 3 views
  • 14 Oct, 2021
  • 1 location
Postoperative Hypoxia and Body Position

The study aims at investigate whether the oxygen partial pressure is improved in the prone position postoperative after abdominal surgery. Included are 50 adults operated with abdominal surgery. The Intervention is turning from supine to prone position and then back to supine position while measuring whether an improvement occurs in …

  • 0 views
  • 03 Apr, 2023
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy

This study will apply novel MRI approaches with established sensitivity to tissue oxygen consumption and perfusion to predict hypoxia-associated radiation resistance, manifested as tumor

  • 0 views
  • 29 Aug, 2023
  • 1 location
CEUS Evaluation of Hypoxic Ischemic Injury

contrast-enhanced ultrasound CEUS in bedside monitoring of neonates and infants with hypoxic ischemic injury. Investigational CEUS scan will be performed separately from clinically indicated conventional

hypoxia
  • 8 views
  • 20 Aug, 2023
  • 1 location
Acute Intermittent Hypoxia in Traumatic Brain Injury (AIH)

This study is designed to answer questions related to safety and preliminary efficacy of Acute Intermittent Hypoxia (AIH) in Traumatic Brain Injury (TBI) survivors. First, we aim to establish

traumatic brain injury
coma
  • 0 views
  • 23 May, 2022
  • 1 location
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea

The purpose of this study is to learn about the effect of sleep apnea and low oxygen on muscle strength and lung function in people with chronic spinal cord injury.

hypoxia
spinal cord disorder
spinal cord
  • 0 views
  • 07 Oct, 2022
  • 1 location
Accuracy of Pulse Oximeters During Profound Hypoxia (APO)

, pulse rate and respiratory rate during hypoxia will be calculated by using data of well-known reference devices, including: A reference SpO2 sensor of Nellcor placed at a fingertip, that

Accepts healthy volunteers
  • 0 views
  • 05 Apr, 2023