Found 268 clinical trials
A Single Center Study on the Functionality of the Pulse Oximeter and Accelerometer Portions of a Novel Wearable Device
The purpose of this study is to asses the function of an oxygen sensor and the movement sensor in a novel device prototype.
- 0 views
- 20 Oct, 2022
- 1 location
Phase I Clinical Trial to Determine the Safety of Clonidine in Infants With HIE During Therapeutic Hypothermia.
Hypoxic ischemic encephalopathy (HIE) occurs in ~ 2-4/1000 term infants and is a major cause of neonatal morbidity and mortality. To date, therapeutic hypothermia started within 6 h of birth
- 14 views
- 08 Nov, 2020
- 1 location
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).
- 0 views
- 23 Aug, 2023
- 1 location
Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI
agnostic Hypoxia Activated Prodrug in patients with HRD/FAD solid tumours or tumor types with high incidence of HRD/FAD in monotherapy or in combination with carboplatin or patients with solid tumour and
- 0 views
- 17 Sep, 2023
- 1 location
Adenosine 2A Receptor Antagonism and AIH in ALS
intermittent hypoxia, or AIH), on breathing. This project will study breathing in people with amyotrophic lateral sclerosis (ALS) and unaffected, age-matched adults. Istradefylline is prescribed to increase
- 0 views
- 07 Apr, 2023
- 1 location
TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC) (TACE-Ax-HCQ)
therapy such as TACE has a higher response rate and improves progression-free survival (PFS), but the benefit is still limited. Cancer cells escape ischemic cell death via autophagy and hypoxia-inducible
- 0 views
- 02 Oct, 2023
- 1 location
Amnioinfusion for Intrauterine Neuroprotection
Hypoxic ischemic encephalopathy (HIE), a serious brain injury in infants, occurs in 2-9 per 1,000 infants after delivery. Up to 60% of infants diagnosed with HIE die and 25% of the survivors
- 0 views
- 07 Oct, 2022
- 1 location
Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients (CLOUDIMPP)
improvement of time in target saturations, reduces periods of hyperoxia, and severe hypoxia in preterm infants on positive pressure respiratory support. This study aims to compare the closed-loop FiO2
- 0 views
- 17 Sep, 2023
- 1 location
The Effects of Ketogenic Diet on the Heart and Brain
is that an increased level of ketone bodies will improve energy utilization in the heart by reducing oxygen deficiency in the heart as well as increasing blood flow in the brain. The study
- 0 views
- 27 Aug, 2021
- 1 location
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT
by hypoxic injury. The pharmacological and physiologic effects of HBOT have direct and indirect mechanisms and effects on reactive oxygen species (ROS) most beneficial to that of wound healing and
- 1 views
- 18 Sep, 2021
- 1 location