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Found 291 clinical trials
Influence of Manipulation of Oocytes and Embryos in Low Oxygen Tension on Assisted Reproduction Technology Outcome

Nowadays, most assisted reproduction laboratories attempt to maintain as much as possible ex vivo culture conditions comparable to those in vivo. Various culturing condition such as temperature and pH parameters have been adjusted according to in vivo values in order to improve in-vitro fertilization (IVF) outcomes. Embryos of most mammals, …

  • 13 views
  • 03 Jun, 2021
  • 1 location
Study to Reinforce Immunity (STRI) Phase 2 Clinical Trial

Protocol STRI12 - Study to Reinforce Immunity (STRI) - A Phase 2 Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of STRI Formula in Non-Hospitalized Participants with COVID-19 (the Study)

  • 9 views
  • 07 Oct, 2022
  • 9 locations
Fetal Scalp Stimulation Versus Fetal Blood Sampling in Labour (FIRSST)

Pregnant women have routine monitoring of the baby's heart rate when in labour. Women with complicated pregnancies require continuous monitoring using an electronic recorder called a CTG. The CTG produces a paper based recording which is interpreted by the midwife as showing normal, suspicious or abnormal features of the baby's …

  • 2 views
  • 04 Oct, 2022
  • 1 location
Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk …

  • 3 views
  • 04 Oct, 2022
  • 10 locations
Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

The specific aim of this double blind, randomized phase III trial is to evaluate the safety and efficacy of T89 in preventing Acute Mountain Sickness (AMS) and relieving the symptoms of AMS after rapid ascent.

  • 0 views
  • 16 Aug, 2021
  • 1 location
Rebreathing-induced Hypoxia and Glucose Levels

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Accepts healthy volunteers
  • 0 views
  • 30 Jun, 2022
  • 1 location
Citicoline as Neuroprotector in Neonates Exposed to Hypoxia

Citicoline as neuroprotector in neonates exposed to hypoxia: A randomized controlled trial

  • 0 views
  • 08 Feb, 2022
  • 1 location
Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

This study uses magnetic resonance imaging to determine whether 3 weeks of repeated exposure to Acute Intermittent Hypoxia can improve brain blood flow or blood flow regulation in healthy adults

Accepts healthy volunteers
  • 0 views
  • 22 Oct, 2022
  • 1 location
Delineating Between Pathophysiologic Phenotypes of Hypoxic Ischemic Brain Injury After Cardiac Arrest (DIFFUSION)

The main outcome determinant following cardiac arrest is hypoxic ischemic brain injury. Management has involved increasing the delivery of oxygen to the brain. This logic assumes that oxygen

  • 7 views
  • 03 Jun, 2022
  • 1 location
SuperNO2VA Et Versus Oxygen Face Mask During Deep Sedation (iOXYGENATE)

(PAP) versus oxygen therapy with a facemask during procedural deep sedation in patients considered high risk for hypoxia (ie: BMI ≥30 kg/m2 or documented Obstructive Sleep Apnea.

  • 0 views
  • 04 Oct, 2022
  • 1 location