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Found 409 clinical trials
Influence of Manipulation of Oocytes and Embryos in Low Oxygen Tension on Assisted Reproduction Technology Outcome

Nowadays, most assisted reproduction laboratories attempt to maintain as much as possible ex vivo culture conditions comparable to those in vivo. Various culturing condition such as temperature and pH parameters have been adjusted according to in vivo values in order to improve in-vitro fertilization (IVF) outcomes. Embryos of most mammals, …

  • 03 Jun, 2021
  • 1 location
Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants

thought to be related to hypoxia/hyperoxia and neurodevelopmental impairment in ELGANs. The results of this trial may help to improve the quality of life of ELGANs and reduce the burden of significant

  • 26 Sep, 2021
  • 10 locations
Study to Reinforce Immunity (STRI) Phase 2 Clinical Trial

Protocol STRI12 - Study to Reinforce Immunity (STRI) - A Phase 2 Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of STRI Formula in Non-Hospitalized Participants with COVID-19 (the Study)

  • 19 Nov, 2021
  • 1 location
Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk …

  • 07 Apr, 2022
  • 5 locations
Hypoxic Conditioning in Heart Failure (hypoxheart)

Heart failure impairs quality of life and exercise capacity, despite an optimal medical therapy. Alternative methods, like hypoxic conditioning coupled to exercise training, must be explored and

medical therapy
  • 03 Mar, 2022
  • 1 location
Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride

This is a prospective study designed to determine the safety and value of Hypoxyprobe-1 (pimonidazole hydrochloride (-HCl)) to detect levels of tissue hypoxia in patients presenting with

human chorionic gonadotropin
aortic valve insufficiency
pimonidazole hydrochloride
open surgery
  • 14 Feb, 2022
  • 1 location
Citicoline as Neuroprotector in Neonates Exposed to Hypoxia

Citicoline as neuroprotector in neonates exposed to hypoxia: A randomized controlled trial

  • 08 Feb, 2022
  • 1 location
Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

This study uses magnetic resonance imaging to determine whether 3 weeks of repeated exposure to Acute Intermittent Hypoxia can improve brain blood flow or blood flow regulation in healthy adults

Accepts healthy volunteers
  • 11 May, 2022
  • 1 location
Neuromuscular-Blocking Agents and Hypoxemia During Intubation in Infants (ROC-HYPOX) (ROC-HYPOX)

The prevention of the occurrence of respiratory events is a constant concern in pediatric anesthesia, as these represent the main cause of the anesthesic mortality. These events occur partly during induction of anesthesia and are all the more frequent as the child is young. The French recommendations do not propose …

  • 25 Mar, 2022
  • 2 locations
The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)

The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of inflammatory marker C-reactive protein(CRP), which as independent predictor of atrial fibrillationAF, further lower the incidence of new-onset AF following coronary artery …

  • 23 Feb, 2022
  • 1 location