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Found 88 clinical trials
Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial) (DICE)

while neonates are undergoing therapeutic hypothermia (TH) may be beneficial but also presents therapeutic challenges. While there is evidence from animal models of brain injury and clinical trials in

morphine
analgesia
opioid
pain relieving
  • 0 views
  • 04 Jun, 2022
  • 1 location
Injured Spinal Cord Pressure Evaluation

duraplasty reduces intra spinal pressure more effectively than bone realignment alone. 3. Localised hypothermia reduces intra spinal pressure and improves metabolism. We will develop a novel method

spinal injury
injuries
spinal cord disorder
  • 29 views
  • 26 Jan, 2021
  • 1 location
CT Perfusion (CTP) for Assessment of Poor Neurological Outcome in Comatose Cardiac Arrest Patients (CANCCAP)

therapeutic hypothermia that prevent complete neurological/clinical assessment. A complete and reliable neurological assessment is needed for patient's long-term function and survival. A poor-quality

ct scan
  • 0 views
  • 28 Jun, 2022
  • 1 location
Impact of an Intensive Care Diary on Post-traumatic Stress Disorder After a Resuscitated Sudden Death

hypothermia, new techniques of resuscitation), the prognosis remains drastically poor and less than 50% of the patients admitted alive at hospital will survive to the event at 1 year. Outside all

resuscitation
coma
amnesia
  • 4 views
  • 24 Jan, 2021
  • 2 locations
Effect of Active Warming on Surgical Site Infections

This study evaluates the effect of active warming by maintaining the normothermia during abdominal surgical procedures. The investigators hypothesize that there is no difference in terms of preventing surgical site infections between warm air blown surgical access blanket and underbody blanket.

  • 0 views
  • 27 Apr, 2022
  • 1 location
Intravenous Dexmeditomidine for Prevention of Spinal Anesthesia Induced Shivering.

Intraoperative and post operative shivering is a common problem encountered in operating rooms and recovery suites. Shivering under spinal anesthesia has an incidence of 40-60%. Shivering is not only uncomfortable for the patient; additionally it increases minute oxygen consumption, subjecting the patient to a higher risk of cardiovascular complications. A …

Accepts healthy volunteers
  • 0 views
  • 23 May, 2022
  • 1 location
Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys (HMPO2)

The aim of the study is to evaluate the feasibility of this bubble and surface oxygenation and to determine the optimal timing of surface oxygenation (continuous versus intermittent) as alternative for membrane-oxygenated kidneys, originating from DCD donors, during HMP on early graft function in clinical practice.

  • 0 views
  • 10 Jul, 2022
  • 1 location
Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy

This clinical trial is being done to see if giving surfactant (Curosurf®) will decrease the number of days that infants will need a breathing tube, decrease the days in the critical care unit and decrease the number of days needed in the hospital. The primary hypothesis for this study is …

cold
hlhs
hypoplastic left heart syndrome
  • 6 views
  • 11 May, 2022
  • 1 location
Innovative Technologies for the Treatment of Pulmonary and Heart Failure

The purpose of the program. Formulation of new treatments for heart and pulmonary failure through using organ-replacing technologies. Formulation of a clinical protocol and implementation of treatment methods into clinical practice heart and pulmonary failure using organ-replacing technologies. New methods were created for rehabilitating the function of affected organs after …

vasoconstrictors
cytokines
pao2
procalcitonin
  • 0 views
  • 31 Oct, 2021
  • 1 location
RIC in HIE: A Safety and Feasibility Trial

Remote Ischemic Conditioning has never been studied in neonates with HIE. However, RIC has been studied in animal models of perinatal asphyxia and has shown encouraging results. In neonatal rats with HIE, RIC is associated with reduced sensory motor deficits compared to non-RIC, and repeated cycles in three consecutive days …

  • 0 views
  • 27 May, 2022
  • 1 location