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Found 87 clinical trials
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) of donor hearts. The study will

heart disease
lupus
coagulopathy
organ transplantation
heart transplant
  • 0 views
  • 04 Oct, 2022
  • 12 locations
Rectal Temperature Measurement in Detecting Hypothermia During Hip Arthroscopy

arthroscopy surgery. The aim of this study is to detect local and then general hypothermia that may occur by monitoring the body temperature from the rectal mucosa of patients undergoing hip arthroscopy

  • 0 views
  • 19 Jun, 2022
  • 1 location
Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)

optimization of support. Data from basic research, animal models, and retrospective studies, case series, and small prospective studies suggest that therapeutic hypothermia (TH) similar to that used for

covid-19
sepsis
FIO2
neuromuscular blocking agents
acute respiratory distress
  • 0 views
  • 23 Mar, 2022
  • 11 locations
Systemic Hypothermia in Acute Cervical Spinal Cord Injury

This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33C) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord

  • 56 views
  • 07 Oct, 2021
  • 9 locations
Comparison of Hypothermic Versus Normothermic Ex-vivo Preservation. (DCDNet)

inclusion criteria are randomized 1:1 to hypothermic machine perfusion (HMP) vs normothermic machine perfusion (NMP) and then transplanted. 40 liver grafts from ECD-DBD matching the inclusion

anesthesia
liver disease
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Trial of Intravascular Hypothermia Therapy in Acute Ischemic Stroke Patients

previous domestic and foreign literatures, hypothermia can prevent and treat secondary injury caused by ischemia-reperfusion injury and cerebral edema of acute cerebral ischemia, so as to achieve the role

infarct
ischemia
stroke
  • 0 views
  • 20 Jun, 2022
  • 1 location
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT)

the participants will have their body temperature cooled to slightly lower than normal (mild hypothermia) for a portion of the liver transplant operation, while the other half will have their body

anesthesia
chronic kidney disease
renal injury
acute kidney injury
COPD
  • 38 views
  • 04 Mar, 2022
  • 3 locations
Real-time Monitoring of Kidney Grafts on Hypothermic Machine Perfusion (REMO-HYMAP)

A significant number of deceased donor kidneys donated for transplantation are not used and are thrown away due to lack of ways of checking their condition and function before the operation. This significantly reduces the number of potentially life saving transplants. The researchers wish to run a small pilot study …

  • 0 views
  • 15 Jun, 2022
  • 1 location
Hypothermic Oxygenated Perfusion for Extended Criteria Donors in Liver Transplantation (HOPExt) (HOPExt)

, known to be associated with a higher rate of early allograft dysfunction (EAD) and primary non-function because of a greater vulnerability to ischemia-reperfusion injury. The end-ischemic Hypothermic

reperfusion injury
cold
steatosis
  • 17 views
  • 24 Mar, 2022
  • 7 locations
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

Hypoxic-Ischemic Encephalopathy (HIE) occurs in 20 per 1000 births. Only 47% of neonates treated with the state of the art therapy (induced systemic hypothermia) have normal outcomes. Therefore

base deficit
cytokines
deficit
free radical
hypothermia
  • 108 views
  • 02 Jun, 2022
  • 2 locations