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Found 88 clinical trials
The Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities

This prospective randomized clinical trial will assess the effect of pre-operative convective warming on intra-operative thermoregulation in patients undergoing gastrointestinal or genitourinary surgical procedures with the Tiger anesthesia perioperative protocol.

  • 05 Apr, 2022
  • 1 location
Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients (ANAPOD)

Our goal is to evaluate the efficacy of the Westmed system vs the Bair Hugger Blanket.

Accepts healthy volunteers
  • 20 Jul, 2022
  • 1 location
A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy

The study aims to investigate the safety and tolerability of limb cryocompression in preventing of Chemotherapy-induced Peripheral Neuropathy via a newly developed limb cryocompression device in healthy subjects and cancer patients. The limb cryocompression device will be tested for its safety in delivering limb cryocompression and efficacy in improving the …

Accepts healthy volunteers
  • 18 Nov, 2021
  • 1 location
Emergency Preservation and Resuscitation (EPR) for Cardiac Arrest From Trauma (EPR-CAT)

The goal of this study is to rapidly cool trauma victims who have suffered cardiac arrest from bleeding with a flush of ice-cold sodium chloride to preserve the patient to enable surgical control of bleeding, followed by delayed resuscitation with cardiopulmonary bypass.

  • 08 Jul, 2022
  • 1 location
Branched Aortic Arch Study

This is a study to assess the safety and effectiveness of endovascular treatment of aortic aneurysms involving the proximal aortic arch. The investigational operation involves placing a stent-graft over the aortic aneurysm.

  • 23 Jan, 2022
  • 1 location
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia

Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of surgical stress response. Implementation of ERP has been shown to reduce postoperative complications and shorten the hospital LOS.

Accepts healthy volunteers
  • 09 Aug, 2022
  • 1 location
The IPLA-OVCA Trial, Intra-Peritoneal Local Anaesthetics in Ovarian Cancer (IPLA-OVCA)

Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour. Radical resection of all tumour visible by the naked eye followed by adjuvant chemotherapy is associated with best chance of prolonged survival. …

ovarian cancer stage
cytoreductive surgery
cancer of the ovary
fallopian tube
  • 11 Jul, 2022
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and

life support
induced hypothermia
  • 14 Nov, 2021
  • 60 locations
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest. The

  • 14 Sep, 2022
  • 13 locations