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Found 112 clinical trials
The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology

The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures. Because patients who have undergone Fontan procedures rely on low pressures across the pulmonary vascular bed to maintain cardiac output, vasoactive agents that concomitantly increase …

  • 22 Mar, 2022
  • 2 locations
Noninvasive Continuous Blood Pressure Monitoring for Cesarean Delivery

Noninvasive continuous blood pressure monitoring for preventing post-spinal hypotension during cesarean delivery: A randomized controlled trial

  • 23 Mar, 2022
  • 1 location
Acupuncture for the Treatment of Medication-Dependent Hypotension in Heart Failure

Acupuncture is believed to increase blood pressure in people who struggle with low blood pressure. This is a common problem facing people with heart failure, and sometimes these people need to take medications to artificially increase their blood pressure. This study is designed to determine if using acupuncture in people …

heart failure
congestive heart failure
  • 18 Jul, 2021
  • 1 location
Effects of Blueberries in Older Adults (BnD)

This randomized, parallel-design trial will evaluate specific clinical and physiological effects of whole blueberries in adults 70 years of age or older at a congregate-living facility.

Accepts healthy volunteers
  • 13 May, 2022
Therapeutic Study Evaluating the Efficacy of Noradrenaline in the Prevention of Hypotension Related to Intubation for Cardiac or Thoracic Surgery (EPITUBE-HEART)

Arterial hypotension during general anaesthesia (GA) is a serious event. While hypotension can occur during surgery, it usually occurs following induction of GA (i.e. following the injection of drugs to enable intubation). This is due to the injection of large doses of anaesthetic drugs with a vasodilatory effect over a …

  • 09 May, 2022
  • 1 location
Abdominal Binders to Treat Orthostatic Hypotension in Parkinsonian Syndromes (ABOH-PS)

The purpose of the present clinical trial is to determine whether the use of an elastic abdominal binder is effective in the non-pharmacological management of symptomatic, neurogenic orthostatic hypotension (OH) in individuals suffering from Parkinson's disease (PD) or Parkinson variant multiple system atrophy (MSA-P).

movement disorder
orthostatic hypotension
  • 25 Jan, 2022
  • 1 location
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt University Medical …

pure autonomic failure
systolic blood pressure
parkinson's disease
orthostatic hypotension
  • 16 Jun, 2022
  • 1 location
Effect of EEG-guided General Anesthesia on Cumulative Dose of Norepinephrine

Intraoperative hypotension is common in patients having non-cardiac surgery under general anesthesia and is associated with major postoperative complications including myocardial injury, AKI, and death. Intraoperative hypotension is also common in patients having vascular surgery. To treat intraoperative hypotension, vasopressors - such as norepinephrine - and fluids are used. However, …

vascular surgery
Accepts healthy volunteers
  • 13 Apr, 2022
  • 1 location
The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery

The "Hypotension Prediction Index (HPI)" was established by the Edwards Lifescience Company (Irvine, California, USA) and is CE certified. As part of the Edwards Acumen Decision-Support-Software-Suite the HPI is supported by the minimal invasive FloTrac Sensor. The HPI displays the probability of an occurring hypotension. The software was established with …

assisted ventilation
general anesthesia
  • 19 Nov, 2021
  • 1 location
Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation. The autonomic nervous system plays key parts in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals …

autonomic dysreflexia
spinal injury
spinal cord stimulation
spinal cord disorder
neurologic findings
  • 14 Mar, 2022
  • 1 location