Found 97 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
Neurogenic Orthostatic Hypotension research study with CNS
Neurogenic Orthostatic Hypotension research study with CNS
- 316 views
- 23 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure
A Phase 3, multi-center, open-label study to evaluate the safety and tolerability of ampreloxetine in subjects with primary autonomic failures (MSA, PD, and PAF) and symptomatic nOH over 182 weeks.
- 0 views
- 29 Nov, 2020
- 26 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure
A Phase 3, 22-week, Multi-center, Randomized Withdrawal Study of ampreloxetine in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects with Primary Autonomic Failure
- 11 views
- 25 Nov, 2020
- 66 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Antihypertensive Effect of Simvastatin in Hypertensive Patients
Few trials have investigated the hypotensive effect of the Statins. Most were not specifically aimed at this pleiotropic effect or had methodological problems. The possible hypotensive
- 5 views
- 07 Nov, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Individualized Blood Pressure Management During Endovascular Stroke Treatment
its influence on outcome is limited. Some studies indicate that hypotensive blood pressure drops from the level of the admission blood pressure lead to a worse outcome. Intraprocedural hypotensive
- 0 views
- 15 Oct, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
The Effect of Analgesic Drugs on Respiratory Center
opioid receptor agonist, mainly ACTS on the first and second receptors, binding to the second receptor is weak, in the analgesic, sedative effect, with opioid respiratory depression and hypotensive side
- 0 views
- 24 Jan, 2021
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Efficacy and Tolerance of Flucortac in Patients With Orthostatic Neurogenic Hypotension
To evaluate the efficacy of a 4-week fludrocortisone (FLU) treatment on systolic blood pressure depression after 5 minutes of active orthostatism in patients with neurogenic orthostatic hypotension (HON) symptomatic, despite treatment with non-drug measures with or without midodrine.
- 0 views
- 24 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Cardiology/Vascular Diseases
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Currently Recruiting
The Effect of Ondansetron on Spinal Anesthesia in Caesarean Section
The purpose of this study is to compare the administration of two different doses of ondansetron to placebo to prevent hypotension and bradycardia following spinal anaesthesia. Apart from haemodynamic parameters (blood pressure and heart rate),characters of the spinal blockage (time of onset and regression) will be recorded too.
- 1 views
- 15 Jul, 2019
- 1 location
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Phase 4 trial
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients
Doses of intrathecal bupivacaine based on patients either height or height and weight has shown to lower the risk of maternal hypotension with similar quality of anesthesia compared to conventional doses. In clinical practice there is a tendency of reducing the dose of bupivacaine as either low fixed dose or …
- 0 views
- 24 Jan, 2021
- 2 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension
To evaluate the time to treatment intervention in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Pure Autonomic Failure (PAF), Non-Diabetic Autonomic Neuropathy (NDAN) or Dopamine Beta Hydroxylase (DBH) Deficiency who have been previously stabilized with droxidopa therapy for symptoms of neurogenic orthostatic hypotension (NOH) (dizziness, light-headedness, or feelings …
- 0 views
- 17 Dec, 2020
- 127 locations