hypotensive Clinical Research Trials

Found 97 clinical trials

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Neurogenic Orthostatic Hypotension research study with CNS

316 views
23 Nov, 2020
1 location

Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

A Phase 3, multi-center, open-label study to evaluate the safety and tolerability of ampreloxetine in subjects with primary autonomic failures (MSA, PD, and PAF) and symptomatic nOH over 182 weeks.

0 views
29 Nov, 2020
26 locations

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

A Phase 3, 22-week, Multi-center, Randomized Withdrawal Study of ampreloxetine in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects with Primary Autonomic Failure

11 views
25 Nov, 2020
66 locations

Antihypertensive Effect of Simvastatin in Hypertensive Patients

Few trials have investigated the hypotensive effect of the Statins. Most were not specifically aimed at this pleiotropic effect or had methodological problems. The possible hypotensive

antihypertensive drugs

5 views
07 Nov, 2020
1 location

Individualized Blood Pressure Management During Endovascular Stroke Treatment

its influence on outcome is limited. Some studies indicate that hypotensive blood pressure drops from the level of the admission blood pressure lead to a worse outcome. Intraprocedural hypotensive

0 views
15 Oct, 2020
1 location

The Effect of Analgesic Drugs on Respiratory Center

opioid receptor agonist, mainly ACTS on the first and second receptors, binding to the second receptor is weak, in the analgesic, sedative effect, with opioid respiratory depression and hypotensive side

0 views
24 Jan, 2021
1 location

Efficacy and Tolerance of Flucortac in Patients With Orthostatic Neurogenic Hypotension

To evaluate the efficacy of a 4-week fludrocortisone (FLU) treatment on systolic blood pressure depression after 5 minutes of active orthostatism in patients with neurogenic orthostatic hypotension (HON) symptomatic, despite treatment with non-drug measures with or without midodrine.

0 views
24 Jan, 2021
1 location

The Effect of Ondansetron on Spinal Anesthesia in Caesarean Section

The purpose of this study is to compare the administration of two different doses of ondansetron to placebo to prevent hypotension and bradycardia following spinal anaesthesia. Apart from haemodynamic parameters (blood pressure and heart rate),characters of the spinal blockage (time of onset and regression) will be recorded too.

ondansetron

cesarean section

anesthesia

1 views
15 Jul, 2019
1 location

Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients

Doses of intrathecal bupivacaine based on patients either height or height and weight has shown to lower the risk of maternal hypotension with similar quality of anesthesia compared to conventional doses. In clinical practice there is a tendency of reducing the dose of bupivacaine as either low fixed dose or …

0 views
24 Jan, 2021
2 locations

Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension

To evaluate the time to treatment intervention in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Pure Autonomic Failure (PAF), Non-Diabetic Autonomic Neuropathy (NDAN) or Dopamine Beta Hydroxylase (DBH) Deficiency who have been previously stabilized with droxidopa therapy for symptoms of neurogenic orthostatic hypotension (NOH) (dizziness, light-headedness, or feelings …

0 views
17 Dec, 2020
127 locations

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Found 97 clinical trials