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Found 12 clinical trials
Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy (ANGIOSAFE2)

Experimental data suggest that GLP-1 promote endothelial cell growth and angiogenesis which may have beneficial effects on the cardiovascular system but harmful effects on the retina . This project investigate the possible link between incretin therapy and Severe Diabetic Retinopathy. The prevalence of severe DR in patients exposed to incretin …

antidiabetic agents
retinopathy
hypoglycemic agents
glucagon-like peptide-1
glucagon-like peptide 1
  • 0 views
  • 23 Feb, 2022
  • 1 location
A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes (AWARD-JPN)

The purpose of this study is to evaluate the efficacy and safety of 2 doses of dulaglutide in Japanese participants with type 2 diabetes. The study duration is approximately 58 weeks.

sulfonylurea
body mass index
alpha-glucosidase inhibitor
hemoglobin a1c
  • 0 views
  • 06 May, 2022
  • 43 locations
Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

This is an prospective study to evaluate the effect of gene polymorphisms on therapeutic responses to glucagon like peptide-1 receptor agonist (GLP-1 RA) in patients with T2DM.

body mass index
glucagon
hemoglobin a1c
  • 0 views
  • 03 May, 2022
  • 1 location
Effect of Empagliflozin on Ventricular Repolarization. (EMPATHYHEART)

The present project aims to investigate if the empagliflozin has an antiarrhythmic action. Analyzing the T-wave heterogeneity index, a new electrocardiographic risk marker associated with the prediction of cardiovascular risk, in diabetic patients and coronary artery disease, the investigators will verify if empagliflozin is associated with a reduction in electrical …

myocardial infarction
coronary artery stenosis
diabetes
fasting
infarct
  • 13 views
  • 24 May, 2022
  • 1 location
Loxenatide Plus LNG-IUS in Endometrial Atypical Hyperplasia

To study if polyethylene glycol loxenatide plus levonorgestrel-releasing intrauterine system (LNG-IUS) will improve response rates in patients with endometrial atypical hyperplasia.

levonorgestrel
body mass index
atypical hyperplasia
  • 0 views
  • 26 Mar, 2022
  • 1 location
Enhanced Recovery After Spinal Surgery Protocol Versus Conventional Care in Non Insulin Diabetic Patients ( ERAS )

enhanced recovery after spinal surgery protocol (ERAS) versus conventional care in non insulin diabetic patients. Our hypothesis is that non-insulin dependent diabetic patients who will undergo lumbar decompression surgery following ERAS care may have higher quality of recovery after surgery, lower postoperative pain scores, decreased opioid consumption, reduced Length of …

  • 0 views
  • 24 Sep, 2021
  • 1 location
Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers

The aim of this study is to test the effect of a new drug on the composition of the urine in kidney stone patients. This new drug (Jardiance, substance: empagliflozin) is currently approved in Switzerland for the treatment of patients with diabetes. Data from previous studies with and without diabetes …

Uric Acid Test
diabetes
  • 0 views
  • 05 Nov, 2021
  • 1 location
Westlake Diabetes Cohort

This is a prospective cohort study that takes place in a clinic of Hangzhou, China. The aim of this study is to explore the molecular mechanism of special Chinese medicine formula combined with personalized nutrition to assist the treatment of diabetes from the aspect of multi-omics view. This study also …

  • 0 views
  • 23 Apr, 2022
  • 1 location
A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients

long-term prognosis of patients' quality of life, spinal function and stability of internal fixation. Research shows that hypoglycemic drugs can not only control blood glucose level, but also affect

  • 0 views
  • 01 Jul, 2022
The Role of Skin Microecology in Diabetic Skin Lesions

lesions. The investigators will explore in animal experiments to regulate the influence of skin micro-ecology on diabetic skin lesions through treatment methods such as different hypoglycemic drugs and

Accepts healthy volunteers
diabetic foot
osteomyelitis
diabetes
debridement
  • 0 views
  • 30 May, 2022
  • 1 location