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Found 82 clinical trials
Mechanisms for Restoration of Hypoglycemia Awareness

To assess if using the hypoglycemic clamp and functional magnetic resonance imaging (fMRI) scanning in hypoglycemia unaware and aware T1DM patients and healthy controls have showed distinct

Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location
Randomized Controlled Study to Evaluate the Effect of Hyperbaric Oxygen Therapy (HBOT) on Treg-CD4+Cells, Cytokines Profile, and Beta Cells Reserve in New-onset Type-1 Diabetes Mellitus

-peptide, peak C-peptide, and basal proinsulin/c-peptide ratio. glycemic control parameters will be evaluated by CGMS data regarding time spent in glycemic range, hypoglycemic and hyperglycemic

  • 0 views
  • 18 Oct, 2022
  • 2 locations
Efficacy and Safety of CKD-501 Added to D150 Plus D745 25mg Therapy in Patients With Type 2 Diabetes

The purpose of this study is to prove that the group treated with CKD-501 in combination added that the reduction of glycated hemoglobin superior to placebo treated group added in combination.

  • 1 views
  • 12 Feb, 2022
Effects of Ketosis on Brain Function in Patients With T1DM

The scientific goal of this study is to examine the effects of a ketogenic diet on hypoglycemia tolerance and brain function in people with type 1 diabetes mellitus (T1D) and to clarify the mechanistic role of ketones in this process. Glycemic management of T1D is typified by alternating periods of …

  • 23 views
  • 23 Feb, 2022
The Effect of Donepezil on Wound Healing

The purpose of the study is to test effectiveness of donepezil to improve wound healing in patients with diabetic wounds that have not healed with standard treatment.

  • 0 views
  • 30 Oct, 2021
  • 1 location
Effectiveness of CGMS vs. Self-monitoring Blood Glucose (SMBG) in Woman With Gestational Diabetes

The detection of and control of gestational diabetes carries benefits for both mother and baby related to immediate pregnancy outcomes. The glycemic disorders in diabetes are not solely limited to fasting and postprandial hyperglycemia, but can be extended to the glycemic variability that includes both upward (postprandial glucose increments) and …

  • 0 views
  • 29 Oct, 2021
  • 1 location
Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy (DINE)

Diabetic peripheral neuropathy(DPN) is a length dependent axonal neuropathy that affects at least 50% of patients with diabetes mellitus. DPN is often asymptomatic during the early stages of diabetes ,however, once symptoms and overt deficits have developed, it cannot be reversed. Early diagnosis of neuropathy is important because early diagnosis …

  • 0 views
  • 15 Jun, 2022
  • 1 location
The CGMS in GDM Labor and Delivery Study

Glucose control during labor is important for both fetus and mother. During labor and delivery, the goal is to maintain the sugars in the normal range as safely as possible as increased blood sugars 4-6 h prior to delivery leads to increased rates of hypoglycemia in the neonate. Neonatal hypoglycemia …

Accepts healthy volunteers
  • 0 views
  • 02 Dec, 2021
  • 1 location
Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy (ANGIOSAFE2)

Experimental data suggest that GLP-1 promote endothelial cell growth and angiogenesis which may have beneficial effects on the cardiovascular system but harmful effects on the retina . This project investigate the possible link between incretin therapy and Severe Diabetic Retinopathy. The prevalence of severe DR in patients exposed to incretin …

incretins
glucagon-like peptide 1
hypoglycemic agents
glucagon-like peptide-1
retinopathy
  • 0 views
  • 23 Feb, 2022
  • 1 location
Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus: a Multicenter, Open-label, Randomized, Controlled Trial (DIGNITY Trial)

the present study is to evaluate the durability of glycemic control over 3 years for patients with type 2 diabetes on diet and exercise therapy treated with oral hypoglycemic drug monotherapy.

  • 0 views
  • 12 Oct, 2022
  • 1 location