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Found 363 clinical trials
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Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine if LCZ696 is safe, tolerable and can improve exercise capacity (via improved peak VO2) in non-obstructive HCM patient population over the course of 50 weeks of treatment.

hypertrophy
nt-probnp
exercise test
hypertrophic obstructive cardiomyopathy
cardiopulmonary exercise testing
  • 26 views
  • 28 Oct, 2021
  • 19 locations
None
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

  • 157 views
  • 26 Jan, 2021
  • 98 locations
None
Biventricular Pacing in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy is an inherited condition characterized by thickening (hypertrophy) of the heart muscle. Many patients who have this condition have a reduced ability to

hypertrophy
heart failure
  • 88 views
  • 07 Nov, 2020
  • 1 location
None
Fractional CO2 Laser Treatment of Hypertrophic Scars

Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints. There are also

Accepts healthy volunteers
  • 0 views
  • 17 Oct, 2021
  • 1 location
None
Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant

The hypothesis is that liver venous deprivation (LVD) could strongly improve hypertrophy of the future remnant liver (FRL) at 3 weeks, as compared to portal vein embolization (PVE) in patient

  • 1 views
  • 24 Jan, 2021
  • 12 locations
None
Diastolic Ventricular Interaction and the Effects of Biventricular Pacing in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy, using a Biventricular pacemaker.

hypertrophy
hypertrophic obstructive cardiomyopathy
  • 13 views
  • 07 Nov, 2020
  • 1 location
None
Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

The main aim of this study is to assess the acute effects of a pacemaker on reducing abnormally high intracavity pressures in the hearts of patients with mid-cavity obstructive hypertrophic

hypertrophy
beta blockers
cavity
syncope
hypertrophic obstructive cardiomyopathy
  • 24 views
  • 22 Oct, 2021
  • 1 location
None
A Phase I Study to Assess the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy

This is a randomized, double-blind, placebo-controlled, sequential, 5-day treatment, ascending dose study in subjects with obstructive HCM aged 18-70 years. The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of CT-G20.

  • 8 views
  • 22 Oct, 2021
  • 11 locations
None
Imaging for the Evaluation of Transthyretin Cardiac Amyloidosis Prevalence of Patients Over 65 Hospitalized in Cardiology Wards (the IMPACT Study)

Heart failure with preserved ejection and hypertrophic cardiomyopathy are common diseases and often associated with transthyretin cardiac amyloidosis (TTR-CM), especially in elderly people

  • 0 views
  • 20 Oct, 2021
  • 1 location
None
Trial of Techniques for Umbilical Reconstruction

of post-operative complications such as hypertrophic scar formation will also be measured.

  • 3 views
  • 27 Jan, 2021
  • 1 location