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Found 341 clinical trials
Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine if LCZ696 is safe, tolerable and can improve exercise capacity (via improved peak VO2) in non-obstructive HCM patient population over the course of 50 weeks of treatment.

cpet
nt-probnp
cardiopulmonary exercise testing
hypertrophic obstructive cardiomyopathy
hypertrophy
  • 46 views
  • 21 Mar, 2022
  • 17 locations
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

  • 193 views
  • 26 Jan, 2021
  • 98 locations
Fractional CO2 Laser Treatment of Hypertrophic Scars

Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints. There are also

Accepts healthy volunteers
  • 0 views
  • 17 Oct, 2021
  • 1 location
Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

The main aim of this study is to assess the acute effects of a pacemaker on reducing abnormally high intracavity pressures in the hearts of patients with mid-cavity obstructive hypertrophic

syncope
chest pain
beta blockers
dyspnea
cavity
  • 26 views
  • 27 Feb, 2022
  • 1 location
Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement

Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Imaging for the Evaluation of Transthyretin Cardiac Amyloidosis Prevalence of Patients Over 65 Hospitalized in Cardiology Wards (the IMPACT Study)

Heart failure with preserved ejection and hypertrophic cardiomyopathy are common diseases and often associated with transthyretin cardiac amyloidosis (TTR-CM), especially in elderly people

  • 0 views
  • 20 Oct, 2021
  • 1 location
Trial of Techniques for Umbilical Reconstruction

of post-operative complications such as hypertrophic scar formation will also be measured.

  • 15 views
  • 24 Mar, 2022
  • 1 location
Role of ARNi in Ventricular Remodeling in Hypertensive LVH (REVERSE-LVH)

arteries. As a result of (usually longstanding) hypertension, the heart thickens (i.e. hypertrophies) to maintain function. Ultimately, HF may occur due to long standing energy deficits, muscle injury

  • 0 views
  • 14 May, 2022
  • 1 location
Effects of Blood Flow Restriction Training in Rotator Cuff Related Shoulder Pain

Blood flow restriction training is widespread in sport performance areas, where it has proven to be beneficial in strength and hypertrophy development. However, there are only few studies

  • 0 views
  • 24 Sep, 2021
  • 1 location
Arthroscopic Debridement vs Arthroscopic Hemi-Trapeziectomy on Patients With Thumb Carpometacarpal Joint Osteoarthritis

Patients with thumb carpometacarpal joint osteoarthritis usually suffer from pain, joint enlargement, inflammation, deformity and loss of function. Conservative treatments usually are the first

  • 26 views
  • 23 Feb, 2022
  • 1 location