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Found 1669 clinical trials
An International, Non-Drug Interventional, Real-world Cohort of PAH Patients Newly Initiating PAH Therapy With Guideline-directed Assessments of Disease Severity (CARE PAH)

The purpose of this study is to describe the time to all-cause death and time to death due to pulmonary arterial hypertension (PAH) or first hospitalization due to PAH in the overall study

  • 29 Oct, 2022
  • 36 locations
  • 25 Oct, 2022
  • 34 locations
Clarifying the Optimal Application of SLT Therapy Trial (COAST)

The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting …

  • 04 Oct, 2022
  • 13 locations
The Important Project of Obese Pregnant Women

disabilities, intrauterine fetal death, thromboembolism, gestational diabetes, pregnancy-induced hypertension. Purpose of the project: To assess whether the introduction of new guidelines for overweight

  • 25 Mar, 2022
  • 1 location
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE)

high blood pressure and can damage the heart. Although spironolactone is very effective in patients that do not require dialysis, we do not know if spironolactone is effective in dialysis patients. Our

  • 18 Oct, 2022
  • 60 locations
Twice Against Thrice-weekly Hemodialysis (TATH)

sessions between the two arms, mainly those due to pulmonary edema and hyperkalemia, b) to compare the number of hospitalizations and duration of stay, c) to compare the rate of uncontrolled hypertension

chronic hemodialysis
chronic renal failure
renal replacement therapy
  • 26 Feb, 2022
  • 1 location
Outcome in Patients Treated With Intraarterial Thrombectomy - optiMAL Blood Pressure Control (OPTIMAL-BP)

guideline is adopted even though the possibility of intracerebral hemorrhage or reperfusion injury by high blood pressure. On the other hand, too low blood pressure can worsen cerebral ischemia.

cerebral infarction
arterial occlusion
  • 22 Aug, 2021
  • 1 location
Training Local Leaders to Prevent and Reduce Domestic Violence Evidence From Peru (LIA)

project takes advantage of the randomization of LIA across 250 villages. LIA has two delivery models: a household-based module (HT), consisting of household training sessions by Community Health

Accepts healthy volunteers
  • 04 Oct, 2022
  • 1 location
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …

Accepts healthy volunteers
  • 04 Oct, 2022
  • 29 locations
China Antihypertensive Trial in Acute Ischemic Stroke II (CATIS-2)

The investigators propose to conduct a multicenter randomized trial to test the primary hypothesis of whether early antihypertensive treatment starting between the first 24-48 hours after the onset of an acute ischemic stroke will reduce the risk of composite case-fatality and major disability (modified Rankin Scale score ≥3) at three …

  • 12 May, 2022
  • 1 location