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Found 152 clinical trials
A Phase 1, First Time in Humans Study of NST-1024

A first time in man study of NST-1024

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location
Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia

The purpose of this study is to evaluate the efficacy and safety of ethyl icosapentate in Chinese patients with severe hypertriglyceridemia.

serum triglycerides
icosapent ethyl
fasting
  • 45 views
  • 28 Jun, 2022
  • 1 location
Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment

The purpose of this study is to evaluate the efficacy of Cipros 10 association in the treatment of Dyslipidemia Treatment

  • 0 views
  • 04 Oct, 2022
  • 1 location
Impacts of Lentils on Metabolism and Inflammation

The overall goal of this investigation is to determine gut microbiome dependent and independent impacts of pulse consumption on metabolic resilience and metabolic risk profiles for type 2 diabetes (T2D) and cardiovascular disease (CVD) risk. Specifically, pulse crop consumption has unrealized potential to fundamentally alter how the body responds to …

type 2 diabetes mellitus
diabetes
fasting
serum triglycerides
cardiovascular disease
  • 436 views
  • 19 Jun, 2022
  • 1 location
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol

This study will comprise a randomized controlled, counter-balanced, cross-over trial to evaluate the independent effects of a high cholesterol (high egg), low saturated fat diet and a high saturated fat, low cholesterol diet on blood lipids. Evaluations also include analysis of physical activity as there is emerging evidence that the …

cholesterol level
blood lipids
cholesterol measurement
Accepts healthy volunteers
  • 0 views
  • 17 Mar, 2022
Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion

Dyslipidemia is characterized by low levels of HDLs, hypertriglyceridemia as well as an increases proportion of small dense LDLs. Changes in lipoprotein particles and its concentrations, especially increased levels of pro-atherogenic LDL particles play an important role in the development of cardiovascular diseases. It is well established that statin/PCSK9-inhibitor treatment …

type 2 diabetes mellitus
LDL Cholesterol
dyslipidemia
insulin resistance
cholesterol measurement
  • 84 views
  • 07 Oct, 2022
  • 1 location
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis: (CARE RA)

tailored to patients with RA to improve hyperlipidemia screening and treatment, thereby decreasing the risk for heart attacks and strokes. The aims of this proposal are: Aim 1: To identify

cholesterol measurement
hmg-coa reductase inhibitor
cholesterol level
remission
hmg-coa reductase inhibitors
  • 0 views
  • 24 Mar, 2022
  • 1 location
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects

The purpose of this study is to evaluate the pharmacokinetic characteristics and compare the safety and tolerability after repeated separate or combined administrations of BR1018-1 and BR1018-2 in healthy adults.

body mass index
electrocardiogram
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Role of A2A Receptor in Hypercholesterolemic Patients

Hypercholesterolemia promotes chronic inflammation, endothelial dysfunction, atherosclerosis and is a major risk factor for cardiovascular disease (CVD). Treatment with lipid-lowering drugs (statins, ezetimibe, PCSK9 inhibitors or LDL-apheresis) reduces the risk of major cardiovascular events in proportion to the absolute reduction of LDL-cholesterol (LDL-C). Nevertheless, a better understanding of the effects …

endothelial dysfunction
hypercholesterolemia
cholesterol measurement
pcsk9
ezetimibe
  • 0 views
  • 15 Nov, 2021
  • 1 location
Effect of Oleactiv® on LDL Oxidability (e-POL)

Oleactiv® have previously demonstrated beneficial effects in an animal model of diet-induced atherosclerosis. After a 12-week supplementation, a substantial reduction of aortic fatty streak area has been observed. Also, Oleactiv®-supplemented hamsters displayed significant decrease of both non-HDL-cholesterol and triglycerides levels. Also, phenolic compounds from Oleactiv® demonstrated that increase of cholesterol …

LDL Cholesterol
a 12
hypercholesterolemia
atherosclerosis
cholesterol measurement
  • 0 views
  • 26 Mar, 2022