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Found 195 clinical trials
Featured trial
A long-term 4+ year, double blind placebo controlled study to evaluate the effects of bexagliflozin on hemoglobin A1c in patients with type 2 diabetes and increased risk of cardiovascular adverse events

A long-term 4+ year, double blind placebo controlled study to evaluate the effects of bexagliflozin on hemoglobin A1c in patients with type 2 diabetes and increased risk of cardiovascular adverse events

  • 342 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Kidney Disease in Type 2 Diabetics

Kidney Disease in Type 2 Diabetics

  • 1362 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Diabetic Neuropathy in Type 1 and 2 Diabetics

Diabetic Neuropathy in Type 1 and 2 Diabetics

  • 3000 views
  • 25 Mar, 2021
  • 1 location
Hydration to Optimize Metabolism (H2O-metabolism)

This study evaluates hydration (1.5 L of water daily during 1 year) in the lowering of blood glucose concentration in adults with signs of dehydration (elevated levels of the vasopressin marker copeptin and high urine osmolality). Half of participants will in addition to lifestyle advice receive extra water on top …

Accepts healthy volunteers
  • 8 views
  • 02 Mar, 2022
  • 1 location
Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)

REMD-477 (Volagidemab) is a human anti-glucagon receptor antibody. Its proposed mechanism of action in controlling hyperglycemia is by blocking glucagon receptor (GCGR) signaling. In this way

  • 3 views
  • 25 Nov, 2021
  • 1 location
Effect of Postprandial Insulin Administration of Faster-acting Insulin Analogue Versus Pre-prandial Administration of Acting-insulin Analogue in Cystic Fibrosis Related Diabetes (MIRE)

insulins mimicking the physiological secretion more closely has led to ultra-fast insulins (fast aspart), allowing for postprandial hyperglycaemia to be better controlled. In Type 1 diabetics treated with

  • 0 views
  • 12 May, 2022
  • 1 location
Effectiveness of CGMS vs. Self-monitoring Blood Glucose (SMBG) in Woman With Gestational Diabetes

to fasting and postprandial hyperglycemia, but can be extended to the glycemic variability that includes both upward (postprandial glucose increments) and downward (interprandial glucose decrements

  • 0 views
  • 29 Oct, 2021
  • 1 location
TRE in Type 2 Diabetes (See Food Study 3) (SFS3)

Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers

Accepts healthy volunteers
  • 0 views
  • 09 Jul, 2022
  • 1 location
Comparison of Meal-Time Dosing of Insulin in Cystic Fibrosis Related Diabetes

. If dosed incorrectly, this could lead to marked hyperglycemia and could worsen nutritional status due to urinary glucose losses. In this project, the investigators will perform a within-subjects

  • 13 views
  • 07 Oct, 2022
  • 1 location
Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of Pregnancy

strongly linked to maternal hyperglycemia, both in the peri-conception period and throughout gestation. Although strict glycemic control does improve outcomes, there is still a higher rate of complications

  • 0 views
  • 04 Oct, 2022
  • 1 location