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Found 122 clinical trials
Physical Activity Intervention for Improving Vascular Comorbidity Risk in Multiple Sclerosis

Vascular comorbidities, such as high cholesterol, obesity, high blood pressure, and diabetes, are common among people with multiple sclerosis (MS), and can negatively impact disease diagnosis

diabetes
disease or disorder
relapsing multiple sclerosis
hypertension
  • 4 views
  • 09 Jun, 2022
  • 1 location
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children (FSGS pediatric)

plasma cholesterol level. The system was originally developed for the treatment of patients with serious dyslipidemia such as familial hypercholesterolemia and then applied to improve the dyslipidemia, a

primary focal segmental glomerulosclerosis
kidney transplant
corticosteroids
remission
focal segmental glomerulosclerosis
  • 36 views
  • 20 Apr, 2022
  • 10 locations
Feasibility of a Home Exercise Program to Manage Post-transplant Metabolic Syndrome

intolerance, obesity, hypercholesterolemia and hypertension) has been associated with increased risk for cardiovascular morbidity and long-term survival. Exercise studies in the early post-transplant period

diabetes
insulin resistance
insulin
hypertension
  • 6 views
  • 06 Oct, 2021
  • 1 location
Effect of PCSK9 InhibitorS On Calcific Aortic Valve DiseasE

CAS that are confirmed by echocardiography but currently do not need valve replacement, and with the diagnosis of hypercholesterolemia. All of the patients were followed at 4 weeks24 weeks 48 weeks

stenosis
aortic valve stenosis
  • 0 views
  • 17 Sep, 2021
  • 1 location
Impact of Statin Therapy on Adaptations to Aerobic Exercise

The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.

hmg-coa reductase inhibitor
aspirin
Accepts healthy volunteers
hypertension
  • 6 views
  • 18 May, 2022
  • 1 location
Atorvastatin Therapy on Xanthoma in Alagille Syndrome

To observe the efficacy and safety of atorvastatin on xanthoma in Alagille syndrome through a prospective study.

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.

The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.

Accepts healthy volunteers
  • 8 views
  • 06 Oct, 2021
  • 1 location
Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)

The purpose of this study is to examine how effective rituximab or tocilizumab are in treating side effects for people who are receiving immunotherapy treatment requiring prolonged steroid use. Immune-related side effects are caused by the activation of the immune system. Because rituximab and tocilizumab have been shown to effectively …

  • 0 views
  • 19 Apr, 2022
Ketogenic Diet Following Moderate to Severe Pediatric Traumatic Brain Injury

The primary objective of this study is to evaluate the feasibility and safety of using the ketogenic diet (KD) in children who sustained moderate to severe traumatic brain injury (TBI). The secondary objective is a preliminary evaluation of the outcomes of children who have had the standard of care plus …

amnesia
traumatic brain injury
severe traumatic brain injury
coma
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer (SIMPHONY)

This study recruits patients with metastatic breast cancer who have progressed on their current regimen of dual anti-HER2 therapy. This study evaluates whether or not the addition of simvastatin to the dual anti-HER2 therapy regimen helps make the tumor respond to the anti-HER2 therapy again. All participants will receive simvastatin …

breast cancer
platelet count
endocrine therapy
adenocarcinoma
measurable disease
  • 10 views
  • 18 Apr, 2022
  • 2 locations